GO Term : GO:0043197 dendritic spine GO

Namespace:  cellular_component Obsolete:  false
description  Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

19 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0044459 plasma membrane part Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0044463 cell projection part Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0042995 cell projection A prolongation or process extending from a cell, e.g. a flagellum or axon.
GO:0045202 synapse The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
GO:0044456 synapse part Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
GO:0098589 membrane region A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane.
GO:0098590 plasma membrane region A membrane that is a (regional) part of the plasma membrane.
GO:0097458 neuron part Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
GO:0098794 postsynapse The part of a synapse that is part of the post-synaptic cell.
GO:0043005 neuron projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
GO:0030425 dendrite A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
GO:0036477 somatodendritic compartment The region of a neuron that includes the cell body (cell soma) and the dendrite, but excludes the axon.
GO:0043197 dendritic spine Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.
GO:0044309 neuron spine A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.

30 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0030425 GO:0043197
part of GO:0098794 GO:0043197
is_a GO:0044456 GO:0043197
is_a GO:0044463 GO:0043197
is_a GO:0044309 GO:0043197
has_part GO:0044464 GO:0043197
has_part GO:0016020 GO:0043197
part of GO:0036477 GO:0043197
is_a GO:0044464 GO:0043197
has_part GO:0098589 GO:0043197
is_a GO:0097458 GO:0043197
part of GO:0042995 GO:0043197
part of GO:0043005 GO:0043197
part of GO:0005575 GO:0043197
has_part GO:0044459 GO:0043197
part of GO:0044456 GO:0043197
has_part GO:0005575 GO:0043197
has_part GO:0044425 GO:0043197
part of GO:0044464 GO:0043197
has_part GO:0098590 GO:0043197
part of GO:0045202 GO:0043197
part of GO:0005623 GO:0043197
is_a GO:0005575 GO:0043197
is_a GO:0043005 GO:0043197
is_a GO:0042995 GO:0043197
part of GO:0097458 GO:0043197
part of GO:0043197 GO:0044326
part of GO:0043197 GO:0044327
is_a GO:0043197 GO:0097464
part of GO:0043197 GO:0098836

6 Synonyms

Name Type
stubby dendritic spine synonym
sessile dendritic spine synonym
thin dendritic spine synonym
branched dendritic spine synonym
mushroom dendritic spine synonym
dendrite spine synonym