GO Term : GO:0043316 cytotoxic T cell degranulation GO
Namespace:  biological_process Obsolete:  false
description  The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

50 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006887 exocytosis A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0001906 cell killing Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0051649 establishment of localization in cell The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.
GO:0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules.
GO:0022610 biological adhesion The attachment of a cell or organism to a substrate or other organism.
GO:0046903 secretion The controlled release of a substance by a cell or a tissue.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001775 cell activation A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0016337 single organismal cell-cell adhesion The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
GO:0070489 T cell aggregation The adhesion of one T cell to one or more other T cells via adhesion molecules.
GO:0070486 leukocyte aggregation The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.

62 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0002286 GO:0043316
is_a GO:0043299 GO:0043316
part of GO:0001913 GO:0043316
is_a GO:0002285 GO:0043316
is_a GO:0006887 GO:0043316
part of GO:0001906 GO:0043316
occurs in GO:0005623 GO:0043316
is_a GO:0002366 GO:0043316
is_a GO:0051179 GO:0043316
part of GO:0001909 GO:0043316
is_a GO:0044765 GO:0043316
is_a GO:0044763 GO:0043316
part of GO:0006955 GO:0043316
is_a GO:0046903 GO:0043316
part of GO:0051641 GO:0043316
is_a GO:0022610 GO:0043316
is_a GO:0070489 GO:0043316
is_a GO:0016337 GO:0043316
is_a GO:0045055 GO:0043316
is_a GO:0051649 GO:0043316
is_a GO:0009987 GO:0043316
part of GO:0008150 GO:0043316
is_a GO:0032940 GO:0043316
is_a GO:0071593 GO:0043316
part of GO:0051179 GO:0043316
is_a GO:0098609 GO:0043316
part of GO:0002449 GO:0043316
is_a GO:0045321 GO:0043316
part of GO:0002443 GO:0043316
is_a GO:0002263 GO:0043316

7 Synonyms

Name Type
cytotoxic T cell granule exocytosis synonym
cytotoxic T lymphocyte degranulation synonym
cytotoxic T lymphocyte granule exocytosis synonym
cytotoxic T-cell degranulation synonym
cytotoxic T-cell granule exocytosis synonym
cytotoxic T-lymphocyte degranulation synonym
cytotoxic T-lymphocyte granule exocytosis synonym