GO Term : GO:0043845 DNA polymerase III, proofreading complex GO

Namespace:  cellular_component Obsolete:  false
description  A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

14 Parents

Identifier Name Description
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0009360 DNA polymerase III complex The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:1990234 transferase complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
GO:0061695 transferase complex, transferring phosphorus-containing groups A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0042575 DNA polymerase complex A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
GO:0043845 DNA polymerase III, proofreading complex A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.
GO:0044776 DNA polymerase III, core complex The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044424 GO:0043845
is_a GO:0043234 GO:0043845
part of GO:0044776 GO:0043845
part of GO:0044424 GO:0043845
part of GO:0042575 GO:0043845
part of GO:0043234 GO:0043845
is_a GO:0032991 GO:0043845
part of GO:0044464 GO:0043845
part of GO:0009360 GO:0043845
part of GO:1902494 GO:0043845
is_a GO:0005575 GO:0043845
part of GO:0032991 GO:0043845
part of GO:0005575 GO:0043845
is_a GO:0044464 GO:0043845
part of GO:0061695 GO:0043845
part of GO:1990234 GO:0043845
part of GO:0005623 GO:0043845
part of GO:0005622 GO:0043845

3 Synonyms

Name Type
DNA polymerase III, proof-reading complex synonym
DNA polymerase III, proof-reading subcomplex synonym
DNA polymerase III, proofreading subcomplex synonym