GO Term : GO:0044825 retroviral strand transfer activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

29 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0015074 DNA integration The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0019058 viral life cycle A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.
GO:0016032 viral process A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0044764 multi-organism cellular process Any process that is carried out at the cellular level which involves another organism of the same or different species.
GO:0051704 multi-organism process A biological process which involves another organism of the same or different species.
GO:0044419 interspecies interaction between organisms Any process in which an organism has an effect on an organism of a different species.
GO:0044403 symbiosis, encompassing mutualism through parasitism An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs.
GO:0008907 integrase activity Catalysis of the integration of one segment of DNA into another.
GO:0044826 viral genome integration into host DNA The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.
GO:0044823 retroviral integrase activity Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.
GO:0044825 retroviral strand transfer activity Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.

30 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0044823 GO:0044825
is_a GO:0003824 GO:0044825
part of GO:0044237 GO:0044825
part of GO:0044238 GO:0044825
is_a GO:0003674 GO:0044825
part of GO:0015074 GO:0044825
part of GO:0051704 GO:0044825
part of GO:0044419 GO:0044825
part of GO:0003824 GO:0044825
part of GO:1901360 GO:0044825
part of GO:0019058 GO:0044825
part of GO:0006259 GO:0044825
part of GO:0009987 GO:0044825
part of GO:0006139 GO:0044825
part of GO:0008152 GO:0044825
part of GO:0044403 GO:0044825
part of GO:0016032 GO:0044825
part of GO:0071704 GO:0044825
part of GO:0044826 GO:0044825
part of GO:0008150 GO:0044825
part of GO:0043170 GO:0044825
part of GO:0008907 GO:0044825
part of GO:0006807 GO:0044825
part of GO:0090304 GO:0044825
part of GO:0034641 GO:0044825
part of GO:0044260 GO:0044825
part of GO:0006725 GO:0044825
part of GO:0046483 GO:0044825
part of GO:0003674 GO:0044825
part of GO:0044764 GO:0044825

1 Synonyms

Name Type
strand transfer reaction synonym