GO Term : GO:0045174 glutathione dehydrogenase (ascorbate) activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

22 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0098869 cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0016667 oxidoreductase activity, acting on a sulfur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0098754 detoxification Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
GO:0015038 glutathione disulfide oxidoreductase activity Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
GO:0015037 peptide disulfide oxidoreductase activity Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds.
GO:0015036 disulfide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.
GO:0045174 glutathione dehydrogenase (ascorbate) activity Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0015038 GO:0045174
is_a GO:0016672 GO:0045174
is_a GO:0016209 GO:0045174
part of GO:0009987 GO:0045174
is_a GO:0016491 GO:0045174
is_a GO:0003824 GO:0045174
part of GO:0009636 GO:0045174
is_a GO:0016667 GO:0045174
part of GO:0008150 GO:0045174
is_a GO:0015036 GO:0045174
is_a GO:0015037 GO:0045174
part of GO:0008152 GO:0045174
part of GO:0098869 GO:0045174
part of GO:0042221 GO:0045174
part of GO:0044710 GO:0045174
part of GO:0044699 GO:0045174
is_a GO:0003674 GO:0045174
part of GO:0050896 GO:0045174
part of GO:0098754 GO:0045174
part of GO:0055114 GO:0045174
part of GO:1990748 GO:0045174

8 Synonyms

Name Type
dehydroascorbate reductase activity synonym
dehydroascorbic reductase activity synonym
dehydroascorbic acid reductase activity synonym
GDOR synonym
DHA reductase activity synonym
glutathione:dehydroascorbate oxidoreductase activity synonym
glutathione dehydroascorbate reductase activity synonym
glutathione:dehydroascorbic acid oxidoreductase activity synonym