GO Term : GO:0046851 negative regulation of bone remodeling GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

15 Parents

Identifier Name Description
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
GO:0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
GO:0048771 tissue remodeling The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.
GO:0034103 regulation of tissue remodeling Any process that modulates the frequency, rate, or extent of tissue remodeling.
GO:0034104 negative regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.
GO:0046849 bone remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
GO:0046850 regulation of bone remodeling Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
GO:0046851 negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.

24 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046851 GO:0045779
negatively regulates GO:0046849 GO:0046851
is_a GO:0046850 GO:0046851
is_a GO:0065007 GO:0046851
negatively regulates GO:0046849 GO:0046851
is_a GO:0034104 GO:0046851
is_a GO:0050789 GO:0046851
is_a GO:0051239 GO:0046851
negatively regulates GO:0048771 GO:0046851
is_a GO:0051241 GO:0046851
regulates GO:0048771 GO:0046851
regulates GO:0008150 GO:0046851
negatively regulates GO:0032501 GO:0046851
is_a GO:0034103 GO:0046851
regulates GO:0032501 GO:0046851
is_a GO:0008150 GO:0046851
regulates GO:0044707 GO:0046851
negatively regulates GO:0044707 GO:0046851
negatively regulates GO:0008150 GO:0046851
is_a GO:0048519 GO:0046851
regulates GO:0046849 GO:0046851
regulates GO:0044699 GO:0046851
negatively regulates GO:0044699 GO:0046851
is_a GO:0065007 GO:0046851

4 Synonyms

Name Type
down regulation of bone remodeling synonym
down-regulation of bone remodeling synonym
downregulation of bone remodeling synonym
inhibition of bone remodeling synonym