GO Term : GO:0046603 negative regulation of mitotic centrosome separation GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

53 Parents

Identifier Name Description
GO:0007017 microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GO:0007049 cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0007067 mitotic nuclear division A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
GO:0051301 cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
GO:0051297 centrosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
GO:0051726 regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
GO:0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GO:0031023 microtubule organizing center organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
GO:0000278 mitotic cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0051302 regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0007100 mitotic centrosome separation Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
GO:0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0051783 regulation of nuclear division Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:1902589 single-organism organelle organization An organelle organization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:1903047 mitotic cell cycle process A process that is part of the mitotic cell cycle.
GO:0022402 cell cycle process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
GO:0048285 organelle fission The creation of two or more organelles by division of one organelle.
GO:0000280 nuclear division The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

79 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046602 GO:0046603
is_a GO:0046606 GO:0046603
negatively regulates GO:0007100 GO:0046603
is_a GO:0065007 GO:0046603
negatively regulates GO:0007100 GO:0046603
is_a GO:0045839 GO:0046603
negatively regulates GO:0051301 GO:0046603
regulates GO:0048285 GO:0046603
negatively regulates GO:0000278 GO:0046603
regulates GO:0000226 GO:0046603
regulates GO:0051297 GO:0046603
regulates GO:0051299 GO:0046603
is_a GO:0033043 GO:0046603
is_a GO:0046605 GO:0046603
regulates GO:1903047 GO:0046603
regulates GO:0007098 GO:0046603
negatively regulates GO:0008150 GO:0046603
regulates GO:0007010 GO:0046603
is_a GO:0065007 GO:0046603
is_a GO:0070507 GO:0046603
negatively regulates GO:0044699 GO:0046603
regulates GO:0007017 GO:0046603
negatively regulates GO:0007067 GO:0046603
regulates GO:0044763 GO:0046603
is_a GO:0051783 GO:0046603
regulates GO:0000278 GO:0046603
is_a GO:0051782 GO:0046603
negatively regulates GO:0051299 GO:0046603
negatively regulates GO:0048285 GO:0046603
is_a GO:0051784 GO:0046603

4 Synonyms

Name Type
down-regulation of mitotic centrosome separation synonym
down regulation of mitotic centrosome separation synonym
inhibition of mitotic centrosome separation synonym
downregulation of mitotic centrosome separation synonym