GO Term : GO:0050756 fractalkine metabolic process GO

Namespace:  biological_process Obsolete:  false
description  The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

9 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0042107 cytokine metabolic process The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
GO:0050755 chemokine metabolic process The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0050756 fractalkine metabolic process The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.

14 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0050756 GO:0050751
regulates GO:0050756 GO:0050752
regulates GO:0050756 GO:0050753
negatively regulates GO:0050756 GO:0050753
regulates GO:0050756 GO:0050754
positively regulates GO:0050756 GO:0050754
is_a GO:0050755 GO:0050756
is_a GO:0043170 GO:0050756
is_a GO:0042107 GO:0050756
is_a GO:0044238 GO:0050756
is_a GO:0071704 GO:0050756
is_a GO:0019538 GO:0050756
is_a GO:0008150 GO:0050756
is_a GO:0008152 GO:0050756

9 Synonyms

Name Type
ABCD-3 metabolism synonym
ABCD-3 metabolic process synonym
CX3C membrane-anchored chemokine metabolism synonym
CX3C membrane-anchored chemokine metabolic process synonym
CX3CL1 metabolism synonym
CX3CL1 metabolic process synonym
neurotactin metabolic process synonym
fractalkine metabolism synonym
neurotactin metabolism synonym