GO Term : GO:0051001 negative regulation of nitric-oxide synthase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

27 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0004497 monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0004517 nitric-oxide synthase activity Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
GO:0050999 regulation of nitric-oxide synthase activity Any process that modulates the activity of the enzyme nitric-oxide synthase.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0032768 regulation of monooxygenase activity Any process that modulates the activity of a monooxygenase.
GO:0051341 regulation of oxidoreductase activity Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0032769 negative regulation of monooxygenase activity Any process that stops or reduces the activity of a monooxygenase.
GO:0051354 negative regulation of oxidoreductase activity Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
GO:0051001 negative regulation of nitric-oxide synthase activity Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.

41 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0065007 GO:0051001
is_a GO:0050999 GO:0051001
negatively regulates GO:0004517 GO:0051001
negatively regulates GO:0004517 GO:0051001
is_a GO:0032769 GO:0051001
is_a GO:0048519 GO:0051001
negatively regulates GO:0008152 GO:0051001
negatively regulates GO:0008150 GO:0051001
is_a GO:0043086 GO:0051001
is_a GO:0009892 GO:0051001
regulates GO:0044710 GO:0051001
regulates GO:0044699 GO:0051001
regulates GO:0003674 GO:0051001
negatively regulates GO:0004497 GO:0051001
is_a GO:0051354 GO:0051001
is_a GO:0044092 GO:0051001
regulates GO:0055114 GO:0051001
regulates GO:0016709 GO:0051001
negatively regulates GO:0016491 GO:0051001
negatively regulates GO:0003824 GO:0051001
regulates GO:0016705 GO:0051001
is_a GO:0050789 GO:0051001
regulates GO:0008152 GO:0051001
regulates GO:0008150 GO:0051001
negatively regulates GO:0016705 GO:0051001
is_a GO:0008150 GO:0051001
negatively regulates GO:0016709 GO:0051001
regulates GO:0016491 GO:0051001
regulates GO:0004497 GO:0051001
is_a GO:0065007 GO:0051001

7 Synonyms

Name Type
down regulation of nitric-oxide synthase activity synonym
downregulation of nitric-oxide synthase activity synonym
down-regulation of nitric-oxide synthase activity synonym
negative regulation of NOS activity synonym
inhibition of nitric-oxide synthase activity synonym
NOS inhibitor synonym
nitric-oxide synthase inhibitor synonym