27 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0005634 | nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0005681 | spliceosomal complex | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
| GO:0043234 | protein complex | A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical. |
| GO:0005622 | intracellular | The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0043231 | intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0030529 | intracellular ribonucleoprotein complex | An intracellular macromolecular complex containing both protein and RNA molecules. |
| GO:0030532 | small nuclear ribonucleoprotein complex | A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs. |
| GO:1990904 | ribonucleoprotein complex | A macromolecular complex containing both protein and RNA molecules. |
| GO:0005682 | U5 snRNP | A ribonucleoprotein complex that contains small nuclear RNA U5. |
| GO:0044464 | cell part | Any constituent part of a cell, the basic structural and functional unit of all organisms. |
| GO:0044424 | intracellular part | Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0032991 | macromolecular complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. |
| GO:0005575 | cellular_component | The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. |
| GO:0005623 | cell | The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. |
| GO:0044428 | nuclear part | Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. |
| GO:0043227 | membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0043226 | organelle | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
| GO:0043229 | intracellular organelle | Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0044422 | organelle part | Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane. |
| GO:0044446 | intracellular organelle part | A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. |
| GO:0005684 | U2-type spliceosomal complex | Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. |
| GO:0097525 | spliceosomal snRNP complex | A ribonucleoprotein complex involved in formation of the spliceosome and composed of one or more snRNA and multiple protein components. |
| GO:0000974 | Prp19 complex | A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. |
| GO:0005686 | U2 snRNP | A ribonucleoprotein complex that contains small nuclear RNA U2. |
| GO:0005688 | U6 snRNP | A ribonucleoprotein complex that contains small nuclear RNA U6. |
| GO:0071006 | U2-type catalytic step 1 spliceosome | A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs. |
| GO:0071012 | catalytic step 1 spliceosome | A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
38 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| has_part | GO:0005686 | GO:0071006 |
| has_part | GO:0005688 | GO:0071006 |
| is_a | GO:0071012 | GO:0071006 |
| is_a | GO:0005684 | GO:0071006 |
| has_part | GO:0030532 | GO:0071006 |
| is_a | GO:0044422 | GO:0071006 |
| part of | GO:0005575 | GO:0071006 |
| is_a | GO:0044424 | GO:0071006 |
| is_a | GO:0044446 | GO:0071006 |
| part of | GO:0043226 | GO:0071006 |
| is_a | GO:0005575 | GO:0071006 |
| part of | GO:0043227 | GO:0071006 |
| part of | GO:0005634 | GO:0071006 |
| part of | GO:0043229 | GO:0071006 |
| is_a | GO:0044464 | GO:0071006 |
| has_part | GO:0032991 | GO:0071006 |
| has_part | GO:0005682 | GO:0071006 |
| is_a | GO:1990904 | GO:0071006 |
| has_part | GO:0030529 | GO:0071006 |
| is_a | GO:0030529 | GO:0071006 |
| has_part | GO:0000974 | GO:0071006 |
| part of | GO:0044424 | GO:0071006 |
| has_part | GO:1990904 | GO:0071006 |
| part of | GO:0005623 | GO:0071006 |
| has_part | GO:0097525 | GO:0071006 |
| part of | GO:0005622 | GO:0071006 |
| is_a | GO:0005681 | GO:0071006 |
| part of | GO:0043231 | GO:0071006 |
| has_part | GO:0044428 | GO:0071006 |
| part of | GO:0044464 | GO:0071006 |
