GO Term : GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

76 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GO:0006606 protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.
GO:0006605 protein targeting The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
GO:0006886 intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006913 nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0017038 protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:1902580 single-organism cellular localization A cellular localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0016482 cytoplasmic transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell.
GO:0034613 cellular protein localization Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:1902582 single-organism intracellular transport An intracellular transport which involves only one organism.
GO:0070727 cellular macromolecule localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.

110 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0072479 GO:1901925
is_a GO:0042308 GO:1901925
negatively regulates GO:0044699 GO:1901925
regulates GO:0008150 GO:1901925
regulates GO:0044765 GO:1901925
is_a GO:0065007 GO:1901925
is_a GO:0050794 GO:1901925
regulates GO:0006886 GO:1901925
is_a GO:0090317 GO:1901925
regulates GO:1902593 GO:1901925
is_a GO:0070201 GO:1901925
is_a GO:0071495 GO:1901925
regulates GO:0033365 GO:1901925
regulates GO:0051170 GO:1901925
negatively regulates GO:0006606 GO:1901925
negatively regulates GO:0046907 GO:1901925
negatively regulates GO:0006605 GO:1901925
regulates GO:0006810 GO:1901925
regulates GO:0051179 GO:1901925
regulates GO:0045184 GO:1901925
regulates GO:0034613 GO:1901925
negatively regulates GO:0008104 GO:1901925
negatively regulates GO:0033036 GO:1901925
negatively regulates GO:0051169 GO:1901925
is_a GO:1900181 GO:1901925
is_a GO:1900180 GO:1901925
is_a GO:0008150 GO:1901925
regulates GO:1902580 GO:1901925
negatively regulates GO:0015031 GO:1901925
regulates GO:0044744 GO:1901925

3 Synonyms

Name Type
negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint synonym
KTIP synonym
Kap121p transport inhibitory pathway synonym