GO Term : GO:1902886 negative regulation of proteasome-activating ATPase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

54 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0016887 ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
GO:0042176 regulation of protein catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0042623 ATPase activity, coupled Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0017111 nucleoside-triphosphatase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
GO:0036402 proteasome-activating ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
GO:0032780 negative regulation of ATPase activity Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GO:0032268 regulation of cellular protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

101 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
negatively regulates GO:0036402 GO:1902886
is_a GO:0032780 GO:1902886
is_a GO:0065007 GO:1902886
negatively regulates GO:0036402 GO:1902886
is_a GO:1902885 GO:1902886
regulates GO:0010604 GO:1902886
negatively regulates GO:0019222 GO:1902886
negatively regulates GO:0051246 GO:1902886
regulates GO:0016787 GO:1902886
negatively regulates GO:0050794 GO:1902886
negatively regulates GO:0051247 GO:1902886
is_a GO:0051336 GO:1902886
negatively regulates GO:0003674 GO:1902886
negatively regulates GO:0009896 GO:1902886
negatively regulates GO:0065007 GO:1902886
negatively regulates GO:0009894 GO:1902886
negatively regulates GO:0009893 GO:1902886
regulates GO:0060255 GO:1902886
negatively regulates GO:0016887 GO:1902886
regulates GO:0016818 GO:1902886
negatively regulates GO:0032270 GO:1902886
regulates GO:0016817 GO:1902886
is_a GO:0051346 GO:1902886
negatively regulates GO:0003824 GO:1902886
regulates GO:0017111 GO:1902886
regulates GO:1901800 GO:1902886
negatively regulates GO:0045862 GO:1902886
negatively regulates GO:0060255 GO:1902886
negatively regulates GO:0042623 GO:1902886
regulates GO:1903362 GO:1902886

24 Synonyms

Name Type
inhibition of proteasome-activating ATPase activity synonym
inhibition of proteasome channel opening activity synonym
negative regulation of proteasomal ATPase activity synonym
negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process synonym
negative regulation of proteasome channel opening activity synonym
negative regulation of proteasome channel gating activity synonym
down regulation of proteasomal ATPase activity synonym
down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process synonym
down regulation of proteasome channel opening activity synonym
down regulation of proteasome channel gating activity synonym
down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process synonym
down regulation of proteasome-activating ATPase activity synonym
down-regulation of proteasome channel gating activity synonym
down-regulation of proteasomal ATPase activity synonym
down-regulation of proteasome-activating ATPase activity synonym
down-regulation of proteasome channel opening activity synonym
downregulation of proteasomal ATPase activity synonym
downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process synonym
downregulation of proteasome channel opening activity synonym
downregulation of proteasome channel gating activity synonym
inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process synonym
downregulation of proteasome-activating ATPase activity synonym
inhibition of proteasome channel gating activity synonym
inhibition of proteasomal ATPase activity synonym