GO:0003677
|
DNA binding
|
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0005488
|
binding
|
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0043565
|
sequence-specific DNA binding
|
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
GO:0003676
|
nucleic acid binding
|
Interacting selectively and non-covalently with any nucleic acid. |
GO:0003690
|
double-stranded DNA binding
|
Interacting selectively and non-covalently with double-stranded DNA. |
GO:0008150
|
biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
GO:0003674
|
molecular_function
|
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
GO:0065007
|
biological regulation
|
Any process that modulates a measurable attribute of any biological process, quality or function. |
GO:1901363
|
heterocyclic compound binding
|
Interacting selectively and non-covalently with heterocyclic compound. |
GO:0097159
|
organic cyclic compound binding
|
Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. |
GO:0065009
|
regulation of molecular function
|
Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:0044092
|
negative regulation of molecular function
|
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:1990837
|
sequence-specific double-stranded DNA binding
|
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
GO:0000975
|
regulatory region DNA binding
|
Interacting selectively and non-covalently with a DNA region that regulates a DNA-based process. Such processes include transcription, DNA replication, and DNA repair. |
GO:0001067
|
regulatory region nucleic acid binding
|
Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. |
GO:0000976
|
transcription regulatory region sequence-specific DNA binding
|
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
GO:0044212
|
transcription regulatory region DNA binding
|
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. |
GO:0001012
|
RNA polymerase II regulatory region DNA binding
|
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. |
GO:0000977
|
RNA polymerase II regulatory region sequence-specific DNA binding
|
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. |
GO:0051100
|
negative regulation of binding
|
Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. |
GO:0051098
|
regulation of binding
|
Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. |
GO:0043392
|
negative regulation of DNA binding
|
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). |
GO:0051101
|
regulation of DNA binding
|
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). |
GO:2000677
|
regulation of transcription regulatory region DNA binding
|
Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding. |
GO:2000678
|
negative regulation of transcription regulatory region DNA binding
|
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. |
GO:1903025
|
regulation of RNA polymerase II regulatory region sequence-specific DNA binding
|
Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. |
GO:1903026
|
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
|
Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. |