GO Term : GO:1903124 negative regulation of thioredoxin peroxidase activity GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

39 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0004601 peroxidase activity Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
GO:0016209 antioxidant activity Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0051920 peroxiredoxin activity Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0098869 cellular oxidant detoxification Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0098754 detoxification Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.

61 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0065007 GO:1903124
negatively regulates GO:0008379 GO:1903124
is_a GO:2000469 GO:1903124
is_a GO:1903123 GO:1903124
negatively regulates GO:0008379 GO:1903124
regulates GO:0009987 GO:1903124
regulates GO:0008379 GO:1903124
negatively regulates GO:0016209 GO:1903124
is_a GO:0008150 GO:1903124
is_a GO:0044092 GO:1903124
is_a GO:0051341 GO:1903124
regulates GO:0051920 GO:1903124
negatively regulates GO:0016684 GO:1903124
is_a GO:0048523 GO:1903124
negatively regulates GO:0016491 GO:1903124
regulates GO:0016684 GO:1903124
negatively regulates GO:0044710 GO:1903124
regulates GO:0003674 GO:1903124
negatively regulates GO:0009987 GO:1903124
regulates GO:0004601 GO:1903124
regulates GO:0055114 GO:1903124
is_a GO:2000468 GO:1903124
is_a GO:0051354 GO:1903124
negatively regulates GO:0050896 GO:1903124
is_a GO:0050789 GO:1903124
regulates GO:0044710 GO:1903124
is_a GO:0019222 GO:1903124
negatively regulates GO:0004601 GO:1903124
is_a GO:0048519 GO:1903124
negatively regulates GO:0003674 GO:1903124

19 Synonyms

Name Type
down regulation of thiol peroxidase activity synonym
down regulation of thioredoxin peroxidase activity synonym
down regulation of TPx activity synonym
down regulation of TrxPx activity synonym
down-regulation of thiol peroxidase activity synonym
down-regulation of thioredoxin peroxidase activity synonym
down-regulation of TPx activity synonym
down-regulation of TrxPx activity synonym
downregulation of thiol peroxidase activity synonym
downregulation of thioredoxin peroxidase activity synonym
downregulation of TPx activity synonym
downregulation of TrxPx activity synonym
inhibition of thiol peroxidase activity synonym
inhibition of thioredoxin peroxidase activity synonym
inhibition of TPx activity synonym
inhibition of TrxPx activity synonym
negative regulation of thiol peroxidase activity synonym
negative regulation of TPx activity synonym
negative regulation of TrxPx activity synonym