GO Term : GO:1903467 negative regulation of mitotic DNA replication initiation GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

82 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006260 DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
GO:0006270 DNA replication initiation The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.
GO:0007049 cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0051726 regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006259 DNA metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO:0006261 DNA-dependent DNA replication A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0006275 regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0000278 mitotic cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
GO:0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
GO:0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0090304 nucleic acid metabolic process Any cellular metabolic process involving nucleic acids.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

122 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1903464 GO:1903467
is_a GO:0032297 GO:1903467
is_a GO:1903466 GO:1903467
negatively regulates GO:1902975 GO:1903467
is_a GO:0065007 GO:1903467
negatively regulates GO:1902975 GO:1903467
negatively regulates GO:0006261 GO:1903467
regulates GO:0034641 GO:1903467
negatively regulates GO:0006260 GO:1903467
regulates GO:0071704 GO:1903467
regulates GO:0034645 GO:1903467
negatively regulates GO:0000278 GO:1903467
is_a GO:0051726 GO:1903467
negatively regulates GO:0006139 GO:1903467
negatively regulates GO:0006259 GO:1903467
regulates GO:0006725 GO:1903467
is_a GO:1902576 GO:1903467
is_a GO:0030174 GO:1903467
regulates GO:1902975 GO:1903467
regulates GO:0009059 GO:1903467
regulates GO:0009058 GO:1903467
negatively regulates GO:0008152 GO:1903467
is_a GO:0051171 GO:1903467
is_a GO:0051052 GO:1903467
negatively regulates GO:0008150 GO:1903467
is_a GO:0051172 GO:1903467
is_a GO:0051053 GO:1903467
regulates GO:0046483 GO:1903467
regulates GO:1901360 GO:1903467
regulates GO:1902292 GO:1903467

9 Synonyms

Name Type
downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication synonym
downregulation of DNA replication initiation involved in mitotic DNA replication synonym
inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication synonym
inhibition of DNA replication initiation involved in mitotic DNA replication synonym
negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication synonym
down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication synonym
down regulation of DNA replication initiation involved in mitotic DNA replication synonym
down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication synonym
down-regulation of DNA replication initiation involved in mitotic DNA replication synonym