GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
GO:0051276
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chromosome organization
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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. |
GO:0016568
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chromatin modification
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The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure. |
GO:0006464
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cellular protein modification process
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The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). |
GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
GO:0016570
|
histone modification
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The covalent alteration of one or more amino acid residues within a histone protein. |
GO:0043412
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macromolecule modification
|
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. |
GO:0044238
|
primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
GO:0006482
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protein demethylation
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The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. |
GO:0050790
|
regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
GO:0043086
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negative regulation of catalytic activity
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Any process that stops or reduces the activity of an enzyme. |
GO:0044260
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cellular macromolecule metabolic process
|
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
GO:0016043
|
cellular component organization
|
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
GO:0044267
|
cellular protein metabolic process
|
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
GO:0009987
|
cellular process
|
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
GO:0006325
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chromatin organization
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Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. |
GO:0006996
|
organelle organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
GO:0044763
|
single-organism cellular process
|
Any process that is carried out at the cellular level, occurring within a single organism. |
GO:0044699
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single-organism process
|
A biological process that involves only one organism. |
GO:0071840
|
cellular component organization or biogenesis
|
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
GO:1902589
|
single-organism organelle organization
|
An organelle organization which involves only one organism. |
GO:0008150
|
biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
GO:0003674
|
molecular_function
|
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. |
GO:0044710
|
single-organism metabolic process
|
A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism. |
GO:0043170
|
macromolecule metabolic process
|
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
GO:0065007
|
biological regulation
|
Any process that modulates a measurable attribute of any biological process, quality or function. |
GO:0050794
|
regulation of cellular process
|
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |