GO Term : GO:1904221 negative regulation of serine C-palmitoyltransferase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

24 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016746 transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0051338 regulation of transferase activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0051348 negative regulation of transferase activity Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0016408 C-acyltransferase activity Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.
GO:0016409 palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.
GO:0016454 C-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.
GO:0004758 serine C-palmitoyltransferase activity Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.
GO:1904220 regulation of serine C-palmitoyltransferase activity Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.
GO:1904221 negative regulation of serine C-palmitoyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.

37 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
negatively regulates GO:0004758 GO:1904221
is_a GO:1904220 GO:1904221
is_a GO:0051348 GO:1904221
is_a GO:0065007 GO:1904221
negatively regulates GO:0004758 GO:1904221
regulates GO:0003674 GO:1904221
is_a GO:0009892 GO:1904221
regulates GO:0016408 GO:1904221
regulates GO:0016409 GO:1904221
negatively regulates GO:0008152 GO:1904221
negatively regulates GO:0008150 GO:1904221
regulates GO:0016746 GO:1904221
regulates GO:0016747 GO:1904221
is_a GO:0051338 GO:1904221
is_a GO:0050789 GO:1904221
negatively regulates GO:0016740 GO:1904221
is_a GO:0043086 GO:1904221
is_a GO:0019222 GO:1904221
regulates GO:0016454 GO:1904221
regulates GO:0003824 GO:1904221
negatively regulates GO:0003674 GO:1904221
is_a GO:0048519 GO:1904221
regulates GO:0004758 GO:1904221
negatively regulates GO:0016409 GO:1904221
is_a GO:0050790 GO:1904221
negatively regulates GO:0016746 GO:1904221
negatively regulates GO:0016747 GO:1904221
negatively regulates GO:0016408 GO:1904221
is_a GO:0008150 GO:1904221
regulates GO:0008152 GO:1904221

24 Synonyms

Name Type
down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating synonym
down regulation of 3-oxosphinganine synthetase activity synonym
down regulation of serine C-palmitoyltransferase activity synonym
down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity synonym
down-regulation of 3-oxosphinganine synthetase activity synonym
down regulation of SPT synonym
down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity synonym
down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating synonym
down-regulation of SPT synonym
down-regulation of serine C-palmitoyltransferase activity synonym
downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating synonym
downregulation of 3-oxosphinganine synthetase activity synonym
downregulation of serine C-palmitoyltransferase activity synonym
downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity synonym
inhibition of 3-oxosphinganine synthetase activity synonym
downregulation of SPT synonym
inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity synonym
inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating synonym
inhibition of SPT synonym
inhibition of serine C-palmitoyltransferase activity synonym
negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating synonym
negative regulation of 3-oxosphinganine synthetase activity synonym
negative regulation of SPT synonym
negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity synonym