GO Term : GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway GO
Namespace:  molecular_function Obsolete:  false
description  Any ubiquitin-specific protease activity that is involved in negative regulation of ERAD pathway.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

40 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0004843 ubiquitin-specific protease activity Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0036459 ubiquitinyl hydrolase activity Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
GO:0042176 regulation of protein catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
GO:0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0010605 negative regulation of macromolecule metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0080135 regulation of cellular response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

42 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1904455 GO:1904265
part of GO:1904293 GO:1904455
is_a GO:0004843 GO:1904455
part of GO:1904293 GO:1904455
is_a GO:0004843 GO:1904455
is_a GO:0008234 GO:1904455
part of GO:0019222 GO:1904455
part of GO:0050789 GO:1904455
is_a GO:0008233 GO:1904455
part of GO:0048523 GO:1904455
part of GO:0048583 GO:1904455
part of GO:0065007 GO:1904455
part of GO:0008150 GO:1904455
part of GO:0071704 GO:1904455
part of GO:0043170 GO:1904455
part of GO:0060255 GO:1904455
part of GO:0010605 GO:1904455
part of GO:0048585 GO:1904455
part of GO:1903573 GO:1904455
part of GO:0008152 GO:1904455
part of GO:0080134 GO:1904455
part of GO:0080135 GO:1904455
is_a GO:0070011 GO:1904455
is_a GO:0003674 GO:1904455
part of GO:0051246 GO:1904455
part of GO:0048519 GO:1904455
part of GO:0050794 GO:1904455
is_a GO:0036459 GO:1904455
part of GO:0042176 GO:1904455
part of GO:0042177 GO:1904455

140 Synonyms

Name Type
DUB activity involved in negative regulation of ERAD synonym
deubiquitinase activity involved in down regulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase activity involved in down regulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase activity involved in down regulation of ERAD pathway synonym
deubiquitinase activity involved in down regulation of ER-associated degradation pathway synonym
deubiquitinase activity involved in down-regulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase activity involved in down-regulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase activity involved in down-regulation of ERAD pathway synonym
deubiquitinase activity involved in down-regulation of ER-associated degradation pathway synonym
deubiquitinase activity involved in downregulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase activity involved in downregulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase activity involved in downregulation of ERAD pathway synonym
deubiquitinase activity involved in downregulation of ER-associated degradation pathway synonym
deubiquitinase activity involved in inhibition of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase activity involved in inhibition of endoplasmic reticulum-associated degradation synonym
deubiquitinase activity involved in inhibition of ERAD pathway synonym
deubiquitinase activity involved in inhibition of ER-associated degradation pathway synonym
deubiquitinase activity involved in negative regulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase activity involved in negative regulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase activity involved in negative regulation of ERAD pathway synonym
deubiquitinase activity involved in negative regulation of ER-associated degradation pathway synonym
deubiquitinase involved in down regulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase involved in down regulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase involved in down regulation of ERAD pathway synonym
deubiquitinase involved in down regulation of ER-associated degradation pathway synonym
deubiquitinase involved in down-regulation of endoplasmic reticulum-associated protein degradation pathway synonym
deubiquitinase involved in down-regulation of endoplasmic reticulum-associated degradation synonym
deubiquitinase involved in down-regulation of ERAD pathway synonym
deubiquitinase involved in down-regulation of ER-associated degradation pathway synonym
deubiquitinase involved in downregulation of endoplasmic reticulum-associated protein degradation pathway synonym