GO Term : GO:1904283 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

21 Parents

Identifier Name Description
GO:0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
GO:0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune system process.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0002683 negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
GO:0048002 antigen processing and presentation of peptide antigen The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
GO:0002483 antigen processing and presentation of endogenous peptide antigen The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
GO:0019883 antigen processing and presentation of endogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
GO:0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation.
GO:0002578 negative regulation of antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
GO:0002583 regulation of antigen processing and presentation of peptide antigen Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
GO:0002584 negative regulation of antigen processing and presentation of peptide antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
GO:1904282 regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
GO:1904283 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0019885 GO:1904283
is_a GO:0002590 GO:1904283
negatively regulates GO:0019885 GO:1904283
is_a GO:1904282 GO:1904283
is_a GO:0065007 GO:1904283
is_a GO:0002584 GO:1904283
negatively regulates GO:0002376 GO:1904283
regulates GO:0048002 GO:1904283
is_a GO:0002683 GO:1904283
negatively regulates GO:0002474 GO:1904283
is_a GO:0002583 GO:1904283
is_a GO:0002682 GO:1904283
regulates GO:0002483 GO:1904283
is_a GO:0050789 GO:1904283
negatively regulates GO:0008150 GO:1904283
is_a GO:0048519 GO:1904283
regulates GO:0019883 GO:1904283
regulates GO:0019885 GO:1904283
is_a GO:0002577 GO:1904283
is_a GO:0002578 GO:1904283
regulates GO:0019882 GO:1904283
negatively regulates GO:0048002 GO:1904283
regulates GO:0002474 GO:1904283
negatively regulates GO:0002483 GO:1904283
regulates GO:0002376 GO:1904283
is_a GO:0008150 GO:1904283
regulates GO:0008150 GO:1904283
is_a GO:0065007 GO:1904283
negatively regulates GO:0019882 GO:1904283
negatively regulates GO:0019883 GO:1904283

9 Synonyms

Name Type
down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I synonym
down-regulation of endogenous peptide antigen processing and presentation via MHC class I synonym
downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I synonym
downregulation of endogenous peptide antigen processing and presentation via MHC class I synonym
inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I synonym
inhibition of endogenous peptide antigen processing and presentation via MHC class I synonym
negative regulation of endogenous peptide antigen processing and presentation via MHC class I synonym
down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I synonym
down regulation of endogenous peptide antigen processing and presentation via MHC class I synonym