GO Term : GO:1904782 negative regulation of NMDA glutamate receptor activity GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

78 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005216 ion channel activity Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0006811 ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0004871 signal transducer activity Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
GO:0034220 ion transmembrane transport A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
GO:0015075 ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0004888 transmembrane signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0007166 cell surface receptor signaling pathway A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction.
GO:0004970 ionotropic glutamate receptor activity Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0004872 receptor activity Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0005230 extracellular ligand-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0034765 regulation of ion transmembrane transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0022892 substrate-specific transporter activity Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

129 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0065007 GO:1904782
is_a GO:0032413 GO:1904782
negatively regulates GO:0004972 GO:1904782
negatively regulates GO:0004972 GO:1904782
is_a GO:2000310 GO:1904782
is_a GO:2000272 GO:1904782
is_a GO:1900450 GO:1904782
is_a GO:0010469 GO:1904782
is_a GO:0032412 GO:1904782
is_a GO:0032410 GO:1904782
is_a GO:0051051 GO:1904782
negatively regulates GO:0023052 GO:1904782
negatively regulates GO:0050794 GO:1904782
regulates GO:1902578 GO:1904782
regulates GO:0007154 GO:1904782
is_a GO:0043271 GO:1904782
regulates GO:0051716 GO:1904782
negatively regulates GO:0015276 GO:1904782
negatively regulates GO:0044700 GO:1904782
is_a GO:0043269 GO:1904782
regulates GO:0044699 GO:1904782
regulates GO:0035235 GO:1904782
negatively regulates GO:0004888 GO:1904782
negatively regulates GO:0065007 GO:1904782
negatively regulates GO:0005216 GO:1904782
negatively regulates GO:0003674 GO:1904782
regulates GO:0055085 GO:1904782
is_a GO:1900449 GO:1904782
negatively regulates GO:0005215 GO:1904782
regulates GO:0004972 GO:1904782

14 Synonyms

Name Type
down regulation of N-methyl-D-aspartate selective glutamate receptor activity synonym
down regulation of NMDA glutamate receptor activity synonym
down regulation of NMDA receptor synonym
down-regulation of N-methyl-D-aspartate selective glutamate receptor activity synonym
down-regulation of NMDA glutamate receptor activity synonym
down-regulation of NMDA receptor synonym
downregulation of N-methyl-D-aspartate selective glutamate receptor activity synonym
downregulation of NMDA glutamate receptor activity synonym
downregulation of NMDA receptor synonym
inhibition of N-methyl-D-aspartate selective glutamate receptor activity synonym
inhibition of NMDA glutamate receptor activity synonym
inhibition of NMDA receptor synonym
negative regulation of N-methyl-D-aspartate selective glutamate receptor activity synonym
negative regulation of NMDA receptor synonym