GO Term : GO:1990499 raps-insc complex GO

Namespace:  cellular_component Obsolete:  false
description  Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

16 Parents

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005938 cell cortex The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044444 cytoplasmic part Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0044448 cell cortex part Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
GO:0071944 cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GO:0045177 apical part of cell The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
GO:0099738 cell cortex region The complete extent of cell cortex that underlies some some region of the plamsma membrane
GO:0045179 apical cortex The region that lies just beneath the plasma membrane on the apical edge of a cell.
GO:1990499 raps-insc complex Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).

20 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044448 GO:1990499
part of GO:0045179 GO:1990499
is_a GO:0043234 GO:1990499
is_a GO:0044464 GO:1990499
is_a GO:0044424 GO:1990499
is_a GO:0044444 GO:1990499
part of GO:0071944 GO:1990499
part of GO:0099738 GO:1990499
is_a GO:0032991 GO:1990499
part of GO:0044464 GO:1990499
part of GO:0045177 GO:1990499
part of GO:0005938 GO:1990499
part of GO:0005737 GO:1990499
is_a GO:0005575 GO:1990499
part of GO:0005623 GO:1990499
part of GO:0044448 GO:1990499
part of GO:0005622 GO:1990499
part of GO:0044424 GO:1990499
part of GO:0005575 GO:1990499
part of GO:0044444 GO:1990499

2 Synonyms

Name Type
partner of inscuteable-inscuteable complex synonym
Rapsynoid-Inscuteable complex synonym