Protein Domain : IPR015211

Type:  Domain Name:  Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal
Description:  This C-terminal domain is found in peptidases belonging to MEROPS peptidase family M1, particularly: aminopeptidase-1 of Caenorhabditis elegans, aminopeptidase O, aminopeptidase B and the bifunctional leukotriene A4 hydrolase/aminopeptidase. The domain adopts a structure consisting of two layers of parallel alpha-helices, five in the inner layer and four in the outer, arranged in an antiparallel manner, with perpendicular loops containing short helical segments on top. It is required for the formation of a deep cleft harbouring the catalytic Zn2+ site in leukotriene A4 hydrolase []. Short Name:  Peptidase_M1_C

0 Child Features

0 Contains

1 Cross References

Identifier
PF09127

3 Found Ins

DB identifier Type Name
IPR001930 Family Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
IPR012777 Family Leukotriene A4 hydrolase
IPR015571 Family Peptidase M1, aminopeptidase B

3 GO Annotations

GO Term Gene Name
GO:0008237 IPR015211
GO:0008270 IPR015211
GO:0019370 IPR015211

3 Ontology Annotations

GO Term Gene Name
GO:0008237 IPR015211
GO:0008270 IPR015211
GO:0019370 IPR015211

1 Parent Features

DB identifier Type Name
IPR016024 Domain Armadillo-type fold

313 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
82151 D8QYP4 PAC:15408892 Selaginella moellendorffii 616  
evm.model.supercontig_1.280 PAC:16404211 Carica papaya 287  
29923.m000836 B9SD61 PAC:16813691 Ricinus communis 619  
56651.m000021 B9TBS9 PAC:16828955 Ricinus communis 98  
Cucsa.275800.1 PAC:16974027 Cucumis sativus 613  
Cucsa.275790.1 PAC:16974026 Cucumis sativus 613  
orange1.1g009853m PAC:18095411 Citrus sinensis 524  
AT5G13520.1 Q9FY49 PAC:19667377 Arabidopsis thaliana 616  
Thhalv10012982m V4LN74 PAC:20205516 Eutrema salsugineum 616  
Ciclev10030974m V4TCW0 PAC:20805286 Citrus clementina 620  
Lus10023479 PAC:23160520 Linum usitatissimum 423  
Lus10040361 PAC:23173813 Linum usitatissimum 456  
Potri.008G045900.1 B9HM05 PAC:27039094 Populus trichocarpa 622  
Potri.010G215700.1 B9HU04 PAC:26982077 Populus trichocarpa 620  
Gorai.013G024500.1 A0A0D2S703 PAC:26787145 Gossypium raimondii 619  
46084 C1MGE7 PAC:27345034 Micromonas pusilla CCMP1545 957  
96766 C1FF02 PAC:27398763 Micromonas sp RCC299 632  
Thecc1EG043042t1 A0A061FMC8 PAC:27441992 Theobroma cacao 619  
Migut.F01788.1.p A0A022RJ70 PAC:28931693 Mimulus guttatus 613  
Araha.1988s0001.1.p PAC:28858175 Arabidopsis halleri 363  
Cagra.0596s0041.1.p PAC:28920013 Capsella grandiflora 616  
Glyma.20G244100.1.p I1NJ89 PAC:30522688 Glycine max 610  
Brara.B00502.2.p A0A398A8R6 PAC:30610332 Brassica rapa FPsc 413  
Brara.B00502.1.p A0A398A6B6 PAC:30610331 Brassica rapa FPsc 527  
Brara.J02086.1.p A0A397XNV2 PAC:30611738 Brassica rapa FPsc 614  
Bostr.2902s0087.1.p PAC:30656008 Boechera stricta 616  
Cre13.g585900.t1.2 A0A2K3D0P6 PAC:30784723 Chlamydomonas reinhardtii 649  
Medtr1g116230.1 G7IAW9 PAC:31095778 Medicago truncatula 607  
SapurV1A.0038s0280.1.p PAC:31418097 Salix purpurea 598  
SapurV1A.0023s0630.1.p PAC:31413621 Salix purpurea 620  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11175901