Protein Domain : IPR006066

Type:  Binding_site Name:  Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site
Description:  Nitrite reductases and bacterial sulphite reductases catalyse the 6-electron reduction of nitrite (sulphite) to ammonia (sulphide) []. On the basis of physiological function, 2 types of nitritereductase can be defined: the assimilatory type, which is involved in nitrate assimilation (denitrification); and the dissimilatory type, which is responsible for nitrate respiration function. Assimilatory nitritereductases contain a prosthetic group termed sirohaem (an iron tetra-hydroporphyrin of the isobacteriochlorin type, with 8 carboxylic acid-containing peripheral sidechains), and an iron-sulphur cluster. Similarly, thereare 2 types of sulphite reductase: the assimilatory type, which participate in the synthesis of sulphur-containing compounds; and the dissimilatory type, which are terminal reductases in the reduction of sulphate. Assimilatory sulphite reductases can catalyse 6-electron reduction without the formation of free intermediates,while dissimilatory reductases can produce trithionate and thiosulphate in addition to sulphide. Both types of reductase contain sirohaem and iron-sulphur clusters. A region of sequence similarity, about 80amino acids long, is shared by assimilatory nitrite [] and sulphite reductases [, ]. Four conserved Cys residues are suggested to be involved in binding the sirohaem group and/or theiron-sulphur centre []. Short Name:  NO2/SO3_Rdtase_FeS/sirohaem_BS
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PR00397
PS00365

7 Found Ins

DB identifier Type Name
IPR006067 Domain Nitrite/sulphite reductase 4Fe-4S domain
IPR011787 Family Sulphite reductase, ferredoxin dependent
IPR011786 Family Sulphite reductase (NADPH) hemoprotein, beta subunit
IPR012744 Domain Nitrite reductase [NAD(P)H] large subunit, NirB
IPR017121 Family Nitrite reductase [NAD(P)H], large subunit
IPR014261 Family Sulphite reductase, subunit C
IPR017220 Family Sulphite reductase, assimilatory

4 GO Annotations

GO Term Gene Name
GO:0016491 IPR006066
GO:0020037 IPR006066
GO:0051536 IPR006066
GO:0055114 IPR006066

4 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR006066
GO:0020037 IPR006066
GO:0051536 IPR006066
GO:0055114 IPR006066

0 Parent Features

603 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
178021 D8S9G0 PAC:15403859 Selaginella moellendorffii 604  
230718 D8R4B6 PAC:15416111 Selaginella moellendorffii 596  
evm.model.supercontig_62.8 PAC:16424045 Carica papaya 586  
evm.model.supercontig_942.3 PAC:16428828 Carica papaya 364  
29801.m003182 B9RYH9 PAC:16809032 Ricinus communis 587  
30169.m006441 B9RIC6 PAC:16821241 Ricinus communis 689  
Cucsa.143430.1 PAC:16963789 Cucumis sativus 751  
Cucsa.244280.1 A0A0A0L6H3 PAC:16971284 Cucumis sativus 583  
orange1.1g005564m A0A067FDH3 PAC:18124099 Citrus sinensis 691  
orange1.1g005543m A0A067FCS6 PAC:18124100 Citrus sinensis 691  
orange1.1g008202m A0A067F1P0 PAC:18124101 Citrus sinensis 574  
orange1.1g047572m A0A067EXB3 PAC:18100161 Citrus sinensis 595  
AT5G04590.1 Q9LZ66 PAC:19665499 Arabidopsis thaliana 642  
AT2G15620.1 Q39161 PAC:19639682 Arabidopsis thaliana 586  
Thhalv10022613m V4M7L4 PAC:20202375 Eutrema salsugineum 590  
Thhalv10020266m V4NQW9 PAC:20181884 Eutrema salsugineum 645  
Thhalv10020267m V4NQW9 PAC:20181885 Eutrema salsugineum 645  
Thhalv10020269m V4NQW9 PAC:20181883 Eutrema salsugineum 645  
Thhalv10020247m V4M2G9 PAC:20181882 Eutrema salsugineum 655  
Ciclev10028067m V4UAH2 PAC:20812935 Citrus clementina 595  
Ciclev10014382m V4U5K8 PAC:20816702 Citrus clementina 754  
Ciclev10014381m V4UAV9 PAC:20816701 Citrus clementina 754  
Lus10014059 PAC:23156821 Linum usitatissimum 588  
Lus10030131 PAC:23172600 Linum usitatissimum 687  
Lus10009951 PAC:23150117 Linum usitatissimum 687  
Lus10027360 PAC:23145447 Linum usitatissimum 702  
Potri.009G052600.1 A0A2K1Z345 PAC:26985947 Populus trichocarpa 690  
Potri.009G052600.2 A0A2K1Z345 PAC:26985948 Populus trichocarpa 690  
Potri.001G257000.2 A0A2K2C3R0 PAC:27048247 Populus trichocarpa 691  
Potri.001G257000.1 PAC:27048249 Populus trichocarpa 562  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2204158
            1704886
            2670946