1 Child Features
| DB identifier | Type | Name |
|---|---|---|
| IPR026242 | Family | HAUS augmin-like complex subunit 2, metazoa |
| Type: | Family | Name: | HAUS augmin-like complex subunit 2 |
| Description: | This entry represents HAUS augmin-like complex subunit 2 (HAUS2) from animals and plants [, ]. The HAUS (Homologous to AUgmin Subunits) individual subunits have been designated HAUS1 to HAUS8 []. In animals, HAUS augmin-like complex subunit 2 is a component of the HAUS augmin-like complex, which localises to the centrosomes and interacts with the gamma-tubulin ring complex (gamma-TuRC) []. The interaction between augmin and gamm-TuRC is important for spindle microtubule generation and affects the mitotic progression and cytokinesis []. HAUS2 may also increase the tension between spindle and kinetochore allowing for chromosome segregation during mitosis []. The HAUS augmin-like complex subunit 2 was previously known as centrosomal protein of 27 kDa (Cep27).In plants, the augmin complex contains 8 subunits, including two plant-specific subunits []. Despite lacking cetrosomes, the augmin complex in plants plays an important part in gamma-tubulin-dependent MT nucleation and the assembly of microtubule arrays during mitosis []. | Short Name: | HAUS2 |
| DB identifier | Type | Name |
|---|---|---|
| IPR026242 | Family | HAUS augmin-like complex subunit 2, metazoa |
