Protein Domain : IPR007673

Type:  Family Name:  Condensin subunit 1
Description:  This entry includes condensin subunit 1 (CND1). CND1 is a regulatory subunit of the condensin complex (contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG), a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes []. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases [, , ]. Condensin is a multi-subunit protein complex that acts as an essential regulator of chromosome condensation []. It contains both SMC (structural maintenance of chromosomes) and non-SMC subunits. Condensin plays an important role during mitosis in the compaction and resolution of chromosomes to remove and prevent catenations that would otherwise inhibit segregation. This is thought to be acheived by the introducion of positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. During interphase condensin promotes clustering of dispersed loci into subnuclear domains and inhibits associations between homologues. In meiosis, condensin has been shown to influence the number of crossover events by regulating programmed double-strand breaks. Roles in gene regulation and lymphocyte development have also been defined. Short Name:  Condensin_cplx_su1
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0 Child Features

1 Contains

DB identifier Type Name
IPR011989 Domain Armadillo-like helical

1 Cross References

Identifier
PIRSF017127

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0007067 IPR007673
GO:0030261 IPR007673
GO:0005634 IPR007673

3 Ontology Annotations

GO Term Gene Name
GO:0007067 IPR007673
GO:0030261 IPR007673
GO:0005634 IPR007673

1 Parent Features

DB identifier Type Name
IPR026971 Family Condensin subunit 1/Condensin-2 complex subunit D3

212 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
orange1.1g000705m A0A067DQ70 PAC:18104056 Citrus sinensis 1342  
orange1.1g000718m A0A067DYM1 PAC:18104057 Citrus sinensis 1334  
Ciclev10018515m PAC:20808600 Citrus clementina 1342  
Lus10039013 PAC:23150331 Linum usitatissimum 1245  
81844 C1E5S5 PAC:27395319 Micromonas sp RCC299 1380  
Araha.0887s0014.2.p PAC:28841628 Arabidopsis halleri 1321  
Araha.0887s0014.1.p PAC:28841627 Arabidopsis halleri 1326  
Glyma.02G157700.3.p I1JFK4 PAC:30510600 Glycine max 1323  
Glyma.02G157700.2.p K7K8M4 PAC:30510599 Glycine max 1326  
Glyma.02G157700.1.p A0A0R0L415 PAC:30510598 Glycine max 1327  
Medtr1g051230.1 A0A072VHH5 PAC:31096219 Medicago truncatula 1384  
Kalax.0126s0081.1.p PAC:32551330 Kalanchoe laxiflora 1323  
Kalax.0126s0081.2.p PAC:32551331 Kalanchoe laxiflora 1260  
Sphfalx0033s0027.1.p PAC:32625996 Sphagnum fallax 1478  
Pp3c12_12160V3.6.p PAC:32975116 Physcomitrium patens 1544  
Pp3c12_12160V3.1.p A0A2K1JQI1 PAC:32975118 Physcomitrium patens 1495  
Pp3c12_12160V3.3.p PAC:32975117 Physcomitrium patens 1536  
Pp3c12_12160V3.2.p PAC:32975119 Physcomitrium patens 1487  
Pp3c12_12160V3.7.p PAC:32975120 Physcomitrium patens 1105  
Mapoly0022s0167.1.p A0A2R6XD87 PAC:33010906 Marchantia polymorpha 1446  
Brdisv1Bd3-1_r1002595m.p PAC:33312282 Brachypodium distachyon Bd3-1 991  
Brdisv1Bd3-1_r1002596m.p PAC:33312281 Brachypodium distachyon Bd3-1 1273  
Kaladp0045s0189.2.p PAC:35780541 Kalanchoe fedtschenkoi 1328  
Kaladp0045s0189.1.p PAC:35780540 Kalanchoe fedtschenkoi 1334  
Tp57577_TGAC_v2_mRNA20339 PAC:35992088 Trifolium pratense 1329  
DCAR_016876 PAC:36075727 Daucus carota 1332  
AUR62030338-RA PAC:36300526 Chenopodium quinoa 1311  
AUR62040826-RA PAC:36311970 Chenopodium quinoa 1197  
Phvul.007G247800.1.p PAC:37167459 Phaseolus vulgaris 1326  
Potri.006G041500.1.p A0A2K1ZWK8 PAC:37243569 Populus trichocarpa 1334  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12138188
            9774278
            20442714
            11854418
            11136719