Protein Domain : IPR011061

Type:  Domain Name:  Hirudin/antistatin
Description:  Leeches, such as Hirudo medicinalis(Medicinal leech), produce a variety of antihaemostatic proteins that act as proteinase inhibitors. These inhibitors are used to aid the leech in feeding upon its host by blocking blood coagulation [, ]. Examples of these proteins include hirustasin (inhibitor of tissue kallikrein, trypsin, alpha-chymotrypsin, and granulocyte cathepsin G) [], bdellastasin (inhibitor of trypsin, plasmin, and acrosin) [], factor Xa inhibitor antistasin (inhibitor of blood coagulation factor Xa) [], hirudin (thrombin inhibitor), decorsin (inhibitor of platelet aggregation) [] and haemadin (thrombin inhibitor) []. Short Name:  Hirudin/antistatin
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2 Child Features

DB identifier Type Name
IPR024793 Domain Thrombin inhibitor hirudin
IPR004094 Domain Antistasin-like domain

0 Contains

1 Cross References

Identifier
SSF57262

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0004857 IPR011061

1 Ontology Annotations

GO Term Gene Name
GO:0004857 IPR011061

0 Parent Features

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Sevir.9G198700.1.p A0A4U6T7Q5 PAC:32652976 Setaria viridis 51  
Pavir.4KG285400.1.p PAC:37607470 Panicum virgatum 192  
Misin07G092500.1.p PAC:40517833 Miscanthus sinensis 49  
Sevir.9G198700.1.p A0A4U6T7Q5 PAC:40612903 Setaria viridis 51  
SbiBTX642.08G114000.1.p PAC:44433136 Sorghum bicolor BTx642 51  
Spov3_chr2.00458 PAC:45106134 Spinacia oleracea 82  

7 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10512718
            9311976
            11563948
            10368273
            11257492
            8607116
            11851400