Protein Domain : IPR010329

Type:  Family Name:  3-hydroxyanthranilic acid dioxygenase
Description:  Members of this protein family, from both bacteria and eukaryotes, are the enzyme 3-hydroxyanthranilate 3,4-dioxygenase (). It is part of the kynurenine pathway for the degradation of tryptophan and the biosynthesis of nicotinic acid [].The prokaryotic homologue is involved in the 2-nitrobenzoate degradation pathway [].The enzyme acts on the tryptophan metabolite 3-hydroxyanthranilate and produces 2-amino-3-carboxymuconate semialdehyde, which can rearrange spontaneously to quinolinic acid and feed into nicotinamide biosynthesis, or undergo further enzymatic degradation. Short Name:  3hydroanth_dOase

1 Child Features

DB identifier Type Name
IPR016700 Family 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan

1 Contains

DB identifier Type Name
IPR011051 Domain RmlC-like cupin domain

4 Cross Referencess

Identifier
PTHR15497
PF06052
TIGR03037
MF_00825

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0000334 IPR010329
GO:0005506 IPR010329
GO:0055114 IPR010329

3 Ontology Annotations

GO Term Gene Name
GO:0000334 IPR010329
GO:0005506 IPR010329
GO:0055114 IPR010329

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Pp3s32_460V3.1.p PAC:32948362 Physcomitrium patens 180  
Pum0400s0004.1.p A0A1X6NWB8 PAC:38013008 Porphyra umbilicalis 152  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9539135
            12620844