Protein Domain : IPR004621

Type:  Family Name:  Eukaryotic-type methylenetetrahydrofolate reductase
Description:  The enzyme activities methylenetetrahydrofolate reductase () and 5,10-methylenetetrahydrofolate reductase (FADH) () differ in that the former (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while the latter (assigned in many bacteria) is flexible with respect to the acceptor. Both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as one or the other, this family describes the subset of proteins found in eukaryotes, and currently designated methylenetetrahydrofolate reductase (). This protein is an FAD-containing flavoprotein. Short Name:  Fadh2_euk
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0 Child Features

0 Contains

1 Cross References

Identifier
TIGR00677

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004489 IPR004621
GO:0006555 IPR004621
GO:0055114 IPR004621

3 Ontology Annotations

GO Term Gene Name
GO:0004489 IPR004621
GO:0006555 IPR004621
GO:0055114 IPR004621

1 Parent Features

DB identifier Type Name
IPR003171 Family Methylenetetrahydrofolate reductase

550 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
177964 D8S976 PAC:15407924 Selaginella moellendorffii 322  
140106 D8QNN7 PAC:15404251 Selaginella moellendorffii 594  
evm.model.supercontig_9.233 PAC:16428128 Carica papaya 594  
28966.m000545 B9STA4 PAC:16802087 Ricinus communis 609  
Cucsa.194120.2 PAC:16968140 Cucumis sativus 539  
Cucsa.194120.3 PAC:16968141 Cucumis sativus 510  
AT3G59970.1 Q9SE60 PAC:19665199 Arabidopsis thaliana 421  
AT3G59970.3 Q9SE60 PAC:19665198 Arabidopsis thaliana 592  
AT3G59970.2 F4JAK1 PAC:19665200 Arabidopsis thaliana 407  
Thhalv10005854m V4LNQ6 PAC:20190234 Eutrema salsugineum 592  
Thhalv10001367m V4LH12 PAC:20188867 Eutrema salsugineum 594  
Ciclev10019489m V4T4S2 PAC:20808813 Citrus clementina 572  
Ciclev10019406m V4VQH3 PAC:20808812 Citrus clementina 594  
Lus10025610 PAC:23145068 Linum usitatissimum 604  
Potri.017G000300.1 PAC:26984752 Populus trichocarpa 554  
Potri.007G147300.1 B9HG95 PAC:27014467 Populus trichocarpa 608  
Gorai.006G223600.1 A0A0D2QEY3 PAC:26829451 Gossypium raimondii 595  
Gorai.006G223600.4 A0A0D2QEY3 PAC:26829450 Gossypium raimondii 595  
Gorai.011G153400.3 A0A0D2T8L1 PAC:26811531 Gossypium raimondii 459  
Gorai.011G153400.2 A0A0D2VMP2 PAC:26811530 Gossypium raimondii 569  
Gorai.011G153400.4 A0A0D2RMW6 PAC:26811532 Gossypium raimondii 384  
30887 I0YN51 PAC:27394751 Coccomyxa subellipsoidea C-169 342  
Thecc1EG020235t1 A0A061ELE3 PAC:27452591 Theobroma cacao 599  
Thecc1EG020235t4 A0A061EJJ9 PAC:27452594 Theobroma cacao 401  
Thecc1EG020235t3 A0A061ESA5 PAC:27452593 Theobroma cacao 406  
Thecc1EG020235t2 A0A061EKK8 PAC:27452592 Theobroma cacao 478  
Cagra.1517s0045.1.p PAC:28899389 Capsella grandiflora 594  
Cagra.3527s0051.1.p PAC:28898543 Capsella grandiflora 592  
Glyma.04G256100.3.p I1JZE2 PAC:30489032 Glycine max 595  
Glyma.04G256100.4.p A0A0R0KJF0 PAC:30489034 Glycine max 571  

0 Publications