Protein Domain : IPR018028

Type:  Family Name:  Catalase, mono-functional, haem-containing
Description:  Catalases () are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects []. Hydrogen peroxide is produced as a consequence of oxidative cellular metabolism and can be converted to the highly reactive hydroxyl radical via transition metals, this radical being able to damage a wide variety of molecules within a cell, leading to oxidative stress and cell death. Catalases act to neutralise hydrogen peroxide toxicity, and are produced by all aerobic organisms ranging from bacteria to man. Most catalases are mono-functional, haem-containing enzymes, although there are also bifunctional haem-containing peroxidase/catalases () that are closely related to plant peroxidases, and non-haem, manganese-containing catalases () that are found in bacteria []. Based on a phylogenetic analysis, catalases can be classified into clade 1, 2 and 3. Clade 1 contains small subunit catalases from plants and a subset of bacteria; clade 2 contains large subunit catalases from fungi and a second subset of bacteria; and clade 3 contains small subunit catalases from bacteria, fungi, protists, animals, and plants [, ].This entry represents the mono-functional, haem-containing catalases. Short Name:  Catalase
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3 Child Features

DB identifier Type Name
IPR024711 Family Catalase, mono-functional, haem-containing, clades 1 and 3
IPR024712 Family Catalase, mono-functional, haem-containing, clade 2
IPR024168 Family Catalase, SrpA-type, predicted

0 Contains

3 Cross Referencess

Identifier
PTHR11465
PR00067
PS51402

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004096 IPR018028
GO:0020037 IPR018028
GO:0006979 IPR018028
GO:0055114 IPR018028

4 Ontology Annotations

GO Term Gene Name
GO:0004096 IPR018028
GO:0020037 IPR018028
GO:0006979 IPR018028
GO:0055114 IPR018028

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
404656 D8QW03 PAC:15411785 Selaginella moellendorffii 175  
438313 D8QW05 PAC:15420318 Selaginella moellendorffii 484  
79329 D8QW00 PAC:15401293 Selaginella moellendorffii 76  
102601 D8RV94 PAC:15407441 Selaginella moellendorffii 515  
112561 D8SA07 PAC:15414231 Selaginella moellendorffii 51  
112333 D8SAY4 PAC:15412583 Selaginella moellendorffii 115  
140901 D8QT27 PAC:15410518 Selaginella moellendorffii 492  
evm.model.supercontig_26.187 PAC:16415124 Carica papaya 492  
evm.model.supercontig_6.340 PAC:16423532 Carica papaya 494  
evm.model.supercontig_75.61 PAC:16425902 Carica papaya 491  
evm.model.supercontig_84.106 PAC:16427267 Carica papaya 2280  
30169.m006393 B9RI78 PAC:16821193 Ricinus communis 2278  
30170.m014364 B9R8N4 PAC:16822197 Ricinus communis 974  
Cucsa.077510.2 PAC:16955966 Cucumis sativus 446  
Cucsa.077510.3 PAC:16955967 Cucumis sativus 396  
Cucsa.077510.4 PAC:16955968 Cucumis sativus 392  
Cucsa.153560.1 PAC:16964708 Cucumis sativus 2032  
Cucsa.272110.1 PAC:16973664 Cucumis sativus 532  
Cucsa.272120.1 PAC:16973665 Cucumis sativus 489  
orange1.1g037878m A0A067FFJ2 PAC:18128756 Citrus sinensis 2280  
orange1.1g044386m A0A067H2F2 PAC:18092254 Citrus sinensis 598  
AT4G35090.1 P25819 PAC:19644440 Arabidopsis thaliana 492  
AT4G35090.2 F4JM86 PAC:19644441 Arabidopsis thaliana 474  
AT1G20620.4 Q2V4M4 PAC:19653076 Arabidopsis thaliana 377  
AT1G20620.2 F4HUL6 PAC:19653075 Arabidopsis thaliana 427  
AT1G20620.5 B9DG18 PAC:19653074 Arabidopsis thaliana 485  
AT1G20620.1 Q42547 PAC:19653073 Arabidopsis thaliana 492  
Thhalv10025015m V4P2M5 PAC:20195626 Eutrema salsugineum 492  
Thhalv10024932m V4MEF1 PAC:20195625 Eutrema salsugineum 518  
Thhalv10007795m V4KXD8 PAC:20186015 Eutrema salsugineum 405  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11351128
            14745498
            12557185
            9287428