Protein Domain : IPR024712

Type:  Family Name:  Catalase, mono-functional, haem-containing, clade 2
Description:  Catalases () are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects []. Hydrogen peroxide is produced as a consequence of oxidative cellular metabolism and can be converted to the highly reactive hydroxyl radical via transition metals, this radical being able to damage a wide variety of molecules within a cell, leading to oxidative stress and cell death. Catalases act to neutralise hydrogen peroxide toxicity, and are produced by all aerobic organisms ranging from bacteria to man. Most catalases are mono-functional, haem-containing enzymes, although there are also bifunctional haem-containing peroxidase/catalases () that are closely related to plant peroxidases, and non-haem, manganese-containing catalases () that are found in bacteria []. Based on a phylogenetic analysis, catalases can be classified into clade 1, 2 and 3. Clade 1 contains small subunit catalases from plants and a subset of bacteria; clade 2 contains large subunit catalases from fungi and a second subset of bacteria; and clade 3 contains small subunit catalases from bacteria, fungi, protists, animals, and plants [, ].This entry represents clade 2 of the mono-functional, haem-containing catalases. Short Name:  Catalase_clade2
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0 Child Features

0 Contains

1 Cross References

Identifier
PIRSF038927

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004096 IPR024712
GO:0020037 IPR024712
GO:0006979 IPR024712
GO:0055114 IPR024712

4 Ontology Annotations

GO Term Gene Name
GO:0004096 IPR024712
GO:0020037 IPR024712
GO:0006979 IPR024712
GO:0055114 IPR024712

1 Parent Features

DB identifier Type Name
IPR018028 Family Catalase, mono-functional, haem-containing

5 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1009594m.p PAC:33620157 Brachypodium distachyon Pangenome 701  
Brdisv1BdTR11A1046869m.p PAC:35696784 Brachypodium distachyon BdTR11a 690  
Brdisv1BdTR11A1042035m.p PAC:35693266 Brachypodium distachyon BdTR11a 696  
Brdisv1BdTR11A1042447m.p PAC:35691543 Brachypodium distachyon BdTR11a 694  
Isati.5123s0004.1.p PAC:39317285 Isatis tinctoria 798  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11351128
            14745498
            12557185
            9287428