Protein Domain : IPR005814

Type:  Family Name:  Aminotransferase class-III
Description:  Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [] into subfamilies. One of these, called class-III, includes acetylornithine aminotransferase (), which catalyzes the transfer of an amino group from acetylornithine to alpha-ketoglutarate, yielding N-acetyl-glutamic-5-semi-aldehyde and glutamic acid; ornithine aminotransferase (), which catalyzes the transfer of an amino group from ornithine to alpha-ketoglutarate, yielding glutamic-5-semi-aldehyde and glutamic acid; omega-amino acid--pyruvate aminotransferase (), which catalyzes transamination between a variety of omega-amino acids, mono- and diamines, and pyruvate; 4-aminobutyrate aminotransferase () (GABA transaminase), which catalyzes the transfer of an amino group from GABA to alpha-ketoglutarate, yielding succinate semialdehyde and glutamic acid; DAPA aminotransferase (), a bacterial enzyme (bioA), which catalyzes an intermediate step in the biosynthesis of biotin, the transamination of 7-keto-8-aminopelargonic acid to form 7,8-diaminopelargonic acid; 2,2-dialkylglycine decarboxylase (), a Burkholderia cepacia(Pseudomonas cepacia) enzyme (dgdA) that catalyzes the decarboxylating amino transfer of 2,2-dialkylglycine and pyruvate to dialkyl ketone, alanine and carbon dioxide; glutamate-1-semialdehyde aminotransferase () (GSA); Bacillus subtilisaminotransferases yhxA and yodT; Haemophilus influenzaeaminotransferase HI0949; and Caenorhabditis elegansaminotransferase T01B11.2. Short Name:  Aminotrans_3
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9 Child Features

DB identifier Type Name
IPR004639 Family Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase
IPR010164 Family Ornithine aminotransferase
IPR004636 Family Acetylornithine/Succinylornithine transaminase family
IPR004637 Family 2,4-diaminobutyrate 4-transaminase
IPR004631 Family 4-aminobutyrate aminotransferase, eukaryotic
IPR005815 Family Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA
IPR017747 Family Putrescine aminotransferase
IPR004632 Family 4-aminobutyrate aminotransferase, bacterial
IPR017657 Family L-lysine 6-transaminase

1 Contains

DB identifier Type Name
IPR015421 Domain Pyridoxal phosphate-dependent transferase, major region, subdomain 1

4 Cross Referencess

Identifier
PTHR11986
PF00202
PIRSF000521
PS00600

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0008483 IPR005814
GO:0030170 IPR005814

2 Ontology Annotations

GO Term Gene Name
GO:0008483 IPR005814
GO:0030170 IPR005814

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
270846 D8RGS2 PAC:15423279 Selaginella moellendorffii 463  
97066 D8RMD7 PAC:15407573 Selaginella moellendorffii 481  
413615 D8RQV0 PAC:15415962 Selaginella moellendorffii 849  
143081 D8R0S3 PAC:15412589 Selaginella moellendorffii 437  
432609 D8TGJ0 PAC:15404951 Selaginella moellendorffii 109  
139046 D8TGJ1 PAC:15422745 Selaginella moellendorffii 141  
119949 D8SLG9 PAC:15415383 Selaginella moellendorffii 481  
184782 D8T2B1 PAC:15404873 Selaginella moellendorffii 481  
183248 D8SW39 PAC:15420483 Selaginella moellendorffii 476  
169863 D8RBC1 PAC:15405860 Selaginella moellendorffii 474  
evm.TU.contig_38612.1 PAC:16431216 Carica papaya 141  
evm.TU.contig_44118.1 PAC:16431962 Carica papaya 37  
evm.model.supercontig_100.2 PAC:16404731 Carica papaya 129  
evm.model.supercontig_17.2 PAC:16410699 Carica papaya 477  
evm.model.supercontig_331.1 PAC:16417753 Carica papaya 260  
evm.model.supercontig_33.99 PAC:16417747 Carica papaya 477  
evm.model.supercontig_4.152 PAC:16419233 Carica papaya 364  
evm.model.supercontig_4.153 PAC:16419234 Carica papaya 167  
evm.model.supercontig_8.291 PAC:16426587 Carica papaya 502  
evm.model.supercontig_95.64 PAC:16428907 Carica papaya 851  
29728.m000832 B9SLG6 PAC:16806902 Ricinus communis 473  
29980.m000178 B9SZR1 PAC:16814822 Ricinus communis 254  
30169.m006332 B9RI18 PAC:16821133 Ricinus communis 470  
30179.m000578 B9SJR4 PAC:16822887 Ricinus communis 400  
36431.m000016 B9TQ26 PAC:16826924 Ricinus communis 76  
39433.m000014 B9TKF1 PAC:16827195 Ricinus communis 350  
28446.m000003 B9TA13 PAC:16800842 Ricinus communis 95  
29693.m001974 B9S0X8 PAC:16805944 Ricinus communis 473  
28196.m000208 B9T1C9 PAC:16800294 Ricinus communis 404  
28196.m000212 B9T1D3 PAC:16800298 Ricinus communis 113  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1618757