Protein Domain : IPR010985

Type:  Domain Name:  Ribbon-helix-helix
Description:  This entry represents domains with a ribbon-helix-helix core topology consisting of four helices in an open array of two hairpins. Such domains are found in several bacterial and phage repressors, including the Escherichia colimethionine repressor (MetJ), which when combined with S-adenosylmethionine (SAM) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis []. Other bacterial and phage repressors containing domains with a similar fold include the bacterial plasmid-encoded repressors CopG (), the bacterial omega transcription repressor [], and the phage repressors Arc [] and Mnt []. These repressors are usually obligate dimers, which pair through a single N-terminal strand, and possess a C-terminal helix-turn-helix unit []. Short Name:  Ribbon_hlx_hlx
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2 Child Features

DB identifier Type Name
IPR013321 Domain Arc-type ribbon-helix-helix
IPR023453 Domain Methionine repressor MetJ domain

0 Contains

1 Cross References

Identifier
SSF47598

2 Found Ins

DB identifier Type Name
IPR002084 Family Methionine repressor MetJ
IPR016748 Family Transcription regulator, CopG/Arc/MetJ DNA-binding domain-containing, predicted

1 GO Annotation

GO Term Gene Name
GO:0006355 IPR010985

1 Ontology Annotations

GO Term Gene Name
GO:0006355 IPR010985

0 Parent Features

14 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
69311 D8RE19 PAC:15416419 Selaginella moellendorffii 80  
37501.m000023 B9TQ97 PAC:16827023 Ricinus communis 137  
39480.m000022 B9TH19 PAC:16827206 Ricinus communis 148  
46215.m000025 B9TMC4 PAC:16827869 Ricinus communis 130  
55371.m000029 B9TM86 PAC:16828804 Ricinus communis 85  
Glyma.U004800.1.p A0A367GJC0 PAC:30541458 Glycine max 64  
Brdisv1BdTR11A1041815m.p PAC:35694226 Brachypodium distachyon BdTR11a 1237  
Zm00008a017559_P01 PAC:37196069 Zea mays PH207 417  
Zm00001d052189_P001 A0A1D6QE43 PAC:40275285 Zea mays 415  
Dioal.0812s0034.1.p PAC:40950413 Dioscorea alata 272  
ZmPHJ40.04G228500.1.p PAC:41379702 Zea mays PHJ40 415  
ZmPHB47.04G228000.1.p PAC:41414500 Zea mays PHB47 338  
Dioal.05G156400.1.p PAC:43484591 Dioscorea alata 272  
Dioal.05G156400.2.p PAC:43484592 Dioscorea alata 272  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1943695
            9927650
            7999761
            11733997
            15808743