Protein Domain : IPR012348

Type:  Domain Name:  Ribonucleotide reductase-related
Description:  The R2 protein of ribonucleotide reductase catalyses the reduction of all four ribonucleotides to deoxyribonucleotides for use in DNA synthesis. This catalysis involves generating and storing a tyrosyl radical, which is essential for ribonucleotide reduction. The crystal structure consists of a core of four helices in a closed bundle with a left-handed twist and one crossover connection, and a bimetal-ion centre in the middle of the bundle [].This entry represents proteins that are structurally related to the R2 protein of class I ribonucleotide reductase, including the alpha and beta subunits of methane monooxygenase, and delta 9-stearoyl-acyl carrier protein desaturase []. Short Name:  RNR-rel
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0 Child Features

1 Contains

DB identifier Type Name
IPR005803 Conserved_site Stearoyl-ACP desaturase, conserved site

1 Cross References

Identifier
G3DSA:1.10.620.20

4 Found Ins

DB identifier Type Name
IPR005067 Family Fatty acid desaturase, type 2
IPR000358 Family Ribonucleotide reductase small subunit
IPR012078 Family Methane/phenol monooxygenase, hydroxylase component
IPR003430 Family Methane/phenol/toluene hydroxylase

2 GO Annotations

GO Term Gene Name
GO:0016491 IPR012348
GO:0055114 IPR012348

2 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR012348
GO:0055114 IPR012348

1 Parent Features

DB identifier Type Name
IPR009078 Domain Ferritin-like superfamily

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
430564 D8T9T1 PAC:15420883 Selaginella moellendorffii 797  
231587 D8RGS6 PAC:15417651 Selaginella moellendorffii 336  
411153 D8RGR0 PAC:15406296 Selaginella moellendorffii 240  
411132 D8RGN8 PAC:15406254 Selaginella moellendorffii 409  
173451 D8RR36 PAC:15414905 Selaginella moellendorffii 347  
416425 D8RZ87 PAC:15423079 Selaginella moellendorffii 167  
418317 D8S5B7 PAC:15405859 Selaginella moellendorffii 364  
418320 D8S5B9 PAC:15405876 Selaginella moellendorffii 308  
418316 D8S5B6 PAC:15405856 Selaginella moellendorffii 468  
418315 D8S5B5 PAC:15405855 Selaginella moellendorffii 508  
418321 D8S5C0 PAC:15405878 Selaginella moellendorffii 429  
82227 D8QYN8 PAC:15409632 Selaginella moellendorffii 412  
272030 D8SZZ3 PAC:15422939 Selaginella moellendorffii 404  
evm.TU.contig_43776.1 PAC:16431914 Carica papaya 85  
evm.model.supercontig_16.35 PAC:16410068 Carica papaya 218  
evm.model.supercontig_171.12 PAC:16410896 Carica papaya 330  
evm.model.supercontig_49.67 PAC:16421138 Carica papaya 398  
evm.model.supercontig_5.344 PAC:16421467 Carica papaya 440  
evm.model.supercontig_9.373 PAC:16428283 Carica papaya 270  
29726.m003910 B9RSS1 PAC:16806623 Ricinus communis 342  
29929.m004514 B9RM11 PAC:16813755 Ricinus communis 395  
30020.m000203 B9T0X0 PAC:16815707 Ricinus communis 396  
30190.m010924 B9RBH6 PAC:16823287 Ricinus communis 329  
Cucsa.394970.1 A0A0A0LNI4 PAC:16983283 Cucumis sativus 396  
Cucsa.394970.2 A0A0A0LNI4 PAC:16983284 Cucumis sativus 396  
Cucsa.356490.1 PAC:16980309 Cucumis sativus 199  
Cucsa.156130.1 A0A0A0L8R8 PAC:16964841 Cucumis sativus 329  
Cucsa.277640.1 A0A0A0LJR6 PAC:16974106 Cucumis sativus 395  
orange1.1g016230m A0A067H1J6 PAC:18107624 Citrus sinensis 393  
orange1.1g023028m PAC:18105849 Citrus sinensis 288  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8876648
            8749363