Protein Domain : IPR014042

Type:  Domain Name:  Glutathione synthase, alpha-helical, eukaryotic
Description:  This entry represents an alpha-helical domain found in eukaryotic glutathione synthetase () (GSS), a homodimeric enzyme that catalyses the conversion of gamma-L-glutamyl-L-cysteine and glycine to phosphate and glutathione in the presence of ATP. This is the second step in glutathione biosynthesis, the first step being catalysed by gamma-glutamylcysteine synthetase []. In humans, defects in GSS are inherited in an autosomal recessive way and are the cause of severe metabolic acidosis, 5-oxoprolinuria, and increased rate of haemolysis and defective function of the central nervous system. Short Name:  Glutathione_synthase_a-hlx_euk
Paste the following link

0 Child Features

0 Contains

1 Cross References

Identifier
G3DSA:1.10.1080.10

1 Found In

DB identifier Type Name
IPR005615 Family Glutathione synthase, eukaryotic

4 GO Annotations

GO Term Gene Name
GO:0004363 IPR014042
GO:0005524 IPR014042
GO:0016874 IPR014042
GO:0006750 IPR014042

4 Ontology Annotations

GO Term Gene Name
GO:0004363 IPR014042
GO:0005524 IPR014042
GO:0016874 IPR014042
GO:0006750 IPR014042

0 Parent Features

555 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
AT2G35345.1 Q1G3S2 PAC:19638846 Arabidopsis thaliana 99  
Lus10020562 PAC:23172349 Linum usitatissimum 134  
Lus10030557 PAC:23140693 Linum usitatissimum 140  
Gorai.013G236100.1 A0A0D2SJ08 PAC:26790821 Gossypium raimondii 590  
Brara.C01394.1.p A0A397ZXW1 PAC:30616953 Brassica rapa FPsc 490  
evm_27.model.AmTr_v1.0_scaffold00085.8 W1P4X3 PAC:31556284 Amborella trichopoda 520  
Traes_4DL_F13AD3A4B.4 PAC:31969695 Triticum aestivum 157  
Traes_6DS_352313CDF.9 PAC:31959604 Triticum aestivum 268  
Traes_7AL_5D8A7ACA8.1 PAC:31930870 Triticum aestivum 110  
Traes_7AL_5D8A7ACA8.3 PAC:31930872 Triticum aestivum 89  
Eucgr.C01747.1.p A0A059CQC9 PAC:32036080 Eucalyptus grandis 260  
Kalax.1251s0007.1.p PAC:32553175 Kalanchoe laxiflora 372  
Kalax.0045s0045.2.p PAC:32557448 Kalanchoe laxiflora 365  
Kalax.0045s0045.1.p PAC:32557447 Kalanchoe laxiflora 367  
Kalax.0068s0068.1.p PAC:32598214 Kalanchoe laxiflora 490  
Kalax.0859s0003.1.p PAC:32552315 Kalanchoe laxiflora 139  
Kalax.0888s0008.1.p PAC:32561827 Kalanchoe laxiflora 139  
Mapoly0003s0187.1.p A0A2R6XT84 PAC:33009869 Marchantia polymorpha 131  
Zosma32g01010.1 A0A0K9P8F1 PAC:33172148 Zostera marina 798  
Zosma389g00010.1 A0A0K9P4U6 PAC:33174213 Zostera marina 549  
Dusal.0125s00025.1.p PAC:33191826 Dunaliella salina 238  
Brdisv1Tek-41032235m.p PAC:33503409 Brachypodium distachyon Tek-4 126  
Brdisv1Kah-11038798m.p PAC:34372838 Brachypodium distachyon Kah-1 240  
Brdisv1Foz11046471m.p PAC:35045213 Brachypodium distachyon Foz1 265  
Brdisv1Sig21023900m.p PAC:35241743 Brachypodium distachyon Sig2 454  
Kaladp0031s0033.1.p PAC:35744259 Kalanchoe fedtschenkoi 139  
Tp57577_TGAC_v2_mRNA13286 PAC:35990487 Trifolium pratense 960  
Tp57577_TGAC_v2_mRNA5854 PAC:35978783 Trifolium pratense 549  
AUR62037078-RA PAC:36291697 Chenopodium quinoa 421  
AUR62005115-RA PAC:36287891 Chenopodium quinoa 619  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15981742