Protein Domain : IPR017868

Type:  Repeat Name:  Filamin/ABP280 repeat-like
Description:  The many different actin cross-linking proteins share a common architecture, consisting of a globular actin-binding domain and an extended rod. Whereas their actin-binding domains consist of two calponin homology domains (see ), their rods fall into three families.The rod domain of the family including the Dictyostelium discoideum(Slime mould) gelation factor (ABP120) and human filamin (ABP280). It is constructed from tandem repeats of a 100-residue motif that is glycine and proline rich []. The gelation factor's rod contains 6 copies of the repeat, whereas filamin has a rod constructed from 24 repeats. The resolution of the 3D structure of rod repeats from the gelation factor has shown that they consist of a beta-sandwich, formed by two beta-sheets arranged in an immunoglobulin-like fold [, ]. The repeat structure is common to the members of the gelation factor/filamin family.This entry represents the entire filamin/ABP280 repeat. Short Name:  Filamin/ABP280_repeat-like
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF00630
PS50194

2 Found Ins

DB identifier Type Name
IPR014756 Domain Immunoglobulin E-set
IPR013783 Domain Immunoglobulin-like fold

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
412212 D8RKG0 PAC:15409931 Selaginella moellendorffii 1140  
432046 D8TET5 PAC:15422781 Selaginella moellendorffii 1113  
416480 D8RZE9 PAC:15423216 Selaginella moellendorffii 1365  
407438 D8R5L7 PAC:15418976 Selaginella moellendorffii 1810  
evm.model.supercontig_50.170 PAC:16421633 Carica papaya 1129  
evm.model.supercontig_83.41 PAC:16427180 Carica papaya 181  
29904.m002888 B9RWC1 PAC:16812533 Ricinus communis 946  
29657.m000476 B9SUU2 PAC:16804975 Ricinus communis 1059  
29657.m000472 B9SUT8 PAC:16804971 Ricinus communis 369  
29657.m000473 B9SUT9 PAC:16804972 Ricinus communis 248  
Cucsa.256620.1 A0A0A0L421 PAC:16972575 Cucumis sativus 936  
orange1.1g002057m A0A067FWP0 PAC:18109359 Citrus sinensis 974  
AT5G49150.1 F4K4R6 PAC:19669214 Arabidopsis thaliana 914  
AT3G23900.2 F4J5A9 PAC:19659041 Arabidopsis thaliana 934  
AT3G23900.1 F4J5A7 PAC:19659039 Arabidopsis thaliana 987  
AT3G23900.3 F4J5A7 PAC:19659040 Arabidopsis thaliana 987  
Thhalv10002398m V4MXP5 PAC:20196525 Eutrema salsugineum 864  
Thhalv10005444m V4KQV6 PAC:20198910 Eutrema salsugineum 971  
Ciclev10004448m V4S202 PAC:20790329 Citrus clementina 709  
Ciclev10007186m V4S7A3 PAC:20790411 Citrus clementina 1057  
Lus10032590 PAC:23146421 Linum usitatissimum 954  
Lus10025556 PAC:23145065 Linum usitatissimum 950  
Lus10043159 PAC:23168106 Linum usitatissimum 952  
Potri.001G319000.3 A0A2K2C6T9 PAC:27047905 Populus trichocarpa 953  
Potri.001G319000.4 A0A2K2C6T9 PAC:27047906 Populus trichocarpa 953  
Potri.001G319000.2 PAC:27047907 Populus trichocarpa 918  
Potri.001G319000.1 A0A2K2C6T9 PAC:27047904 Populus trichocarpa 953  
Potri.017G058300.4 U5FLQ0 PAC:26983243 Populus trichocarpa 950  
Potri.017G058300.2 U5FLQ0 PAC:26983241 Populus trichocarpa 950  
Potri.017G058300.3 U5FLQ0 PAC:26983240 Populus trichocarpa 950  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9164464
            10467095