Type: | Family | Name: | Diphthine synthase |
Description: | Diphthine synthase (), also known as diphthamide biosynthesis S-adenosylmethionine-dependent methyltransferase, participates in the modification of a specific histidine residue in elongation factor 2 (EF-2) of eukaryotes and archaea to diphthamide. It is required for the methylation step in dipthamide biosynthesis. The protein was characterised in Saccharomyces cerevisiaeand designated DPH5. | Short Name: | Dphthn_synthase |