3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0004129 | IPR013833 |
| GO:0022904 | IPR013833 |
| GO:0016020 | IPR013833 |
| Type: | Domain | Name: | Cytochrome c oxidase, subunit III, 4-helical bundle |
| Description: | Cytochrome c oxidase () is the terminal enzyme of the respiratory chain of mitochondria and many aerobic bacteria. It catalyzes the transfer of electrons from reduced cytochrome c to molecular oxygen:4 cytochrome c+2+ 4 H++ O2-->4 cytochrome c+3+ 2 H2OThis reaction is coupled to the pumping of four additional protons across the mitochondrial or bacterial membrane [, ]. Cytochrome c oxidase is an oligomeric enzymatic complex that is located in the mitochondrial inner membrane of eukaryotes and in the plasma membrane of aerobic prokaryotes. The core structure of prokaryotic and eukaryotic cytochrome c oxidase contains three common subunits, I, II and III. In prokaryotes, subunits I and III can be fused and a fourth subunit is sometimes found, whereas in eukaryotes there are a variable number of additional small polypeptidic subunits []. The functional role of subunit III is not yet understood.Subunit III of cytochrome c oxidase has a core structure consisting of 6-7 transmembrane alpha-helices organised into two bundles, one bundle formed by the first two helices and the other by the remaining helices. This entry represents the 4-5 alpha-helical bundle. | Short Name: | Cyt_c_oxidase_su3_a-hlx |
| GO Term | Gene Name |
|---|---|
| GO:0004129 | IPR013833 |
| GO:0022904 | IPR013833 |
| GO:0016020 | IPR013833 |
