Protein Domain : IPR008220

Type:  Family Name:  Homoserine acetyltransferase
Description:  Homoserine acetyltransferase (homoserine transacetylase) catalyses the first step unique to methionine biosynthesis, converting L-homoserine to O-acetyl-L-homoserine using acetyl-CoA as an acetyl group donor []. This enzyme regulates homoserine in a number of biosynthetic pathways, making it vital to cell growth and viability. The biosynthesis of methionine in particular has been shown to be susceptible to small-molecule inhibition in fungi and is consequently a good candidate for antifungal agents []. Short Name:  Homoserine_AcTrfase

0 Child Features

1 Contains

DB identifier Type Name
IPR000073 Domain Alpha/beta hydrolase fold-1

3 Cross Referencess

Identifier
PIRSF000443
TIGR01392
MF_00296

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004414 IPR008220
GO:0009086 IPR008220
GO:0005737 IPR008220

3 Ontology Annotations

GO Term Gene Name
GO:0004414 IPR008220
GO:0009086 IPR008220
GO:0005737 IPR008220

0 Parent Features

10 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
406061 D8R0J5 PAC:15413069 Selaginella moellendorffii 366  
35986 I0Z1R6 PAC:27387548 Coccomyxa subellipsoidea C-169 372  
70871 C1N2Q8 PAC:27339313 Micromonas pusilla CCMP1545 944  
203886 PAC:27347435 Micromonas pusilla CCMP1545 526  
55736 C1DZ30 PAC:27396553 Micromonas sp RCC299 939  
58598 C1E6A7 PAC:27395574 Micromonas sp RCC299 530  
10204 A4RXG8 PAC:27416782 Ostreococcus lucimarinus 337  
Brdisv1pangenome1010915m.p PAC:33656971 Brachypodium distachyon Pangenome 330  
Brdisv1BdTR11A1049021m.p PAC:35695904 Brachypodium distachyon BdTR11a 330  
Brdisv1BdTR11A1041081m.p PAC:35692450 Brachypodium distachyon BdTR11a 588  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10913262
            17353245