Protein Domain : IPR013178

Type:  Family Name:  Histone acetyltransferase Rtt109/CBP
Description:  Histone acetylation is required in many cellular processes including transcription, DNA repair, and chromatin assembly. This family contains the fungal RTT109 protein, which is required for H3K56 acetylation []. In Schizosaccharomyces pombe(Fission yeast) loss of RTT109 results in the loss of H3K56 acetylation, both on bulk histone and on chromatin []. RTT109 and H3K56 acetylation appear to correlate with actively transcribed genes and associate with the elongating form of Pol II in yeast []. This family also includes p300/CBP acetyltransferase, which has different catalytic properties and cofactor regulation to RTT109 []. CREB-binding protein (CBP) is a transcriptional co-activator that acetylates both histones and non-histone proteins [, , ]. CBP binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes [, ]. Short Name:  Histone_AcTrfase_Rtt109/CBP
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1 Child Features

DB identifier Type Name
IPR016849 Family Histone acetyltransferase Rtt109

0 Contains

1 Cross References

Identifier
PF08214

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004402 IPR013178
GO:0006355 IPR013178
GO:0016573 IPR013178

3 Ontology Annotations

GO Term Gene Name
GO:0004402 IPR013178
GO:0006355 IPR013178
GO:0016573 IPR013178

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
60640 PAC:15414912 Selaginella moellendorffii 662  
180368 PAC:15412552 Selaginella moellendorffii 1015  
evm.model.supercontig_10.17 PAC:16404526 Carica papaya 1761  
evm.model.supercontig_818.3 PAC:16427039 Carica papaya 567  
30169.m006595 B9RHR9 PAC:16821394 Ricinus communis 1720  
29673.m000917 B9SJ01 PAC:16805309 Ricinus communis 1446  
Cucsa.323340.1 A0A0A0L615 PAC:16977939 Cucumis sativus 1698  
orange1.1g000320m A0A067FV75 PAC:18111490 Citrus sinensis 1673  
orange1.1g000411m A0A067FUK1 PAC:18111492 Citrus sinensis 1553  
orange1.1g000262m A0A067FI89 PAC:18111489 Citrus sinensis 1768  
orange1.1g000333m A0A067FLV5 PAC:18111491 Citrus sinensis 1650  
orange1.1g000748m PAC:18094250 Citrus sinensis 1303  
AT3G12980.1 Q9LE42 PAC:19663097 Arabidopsis thaliana 1670  
AT1G16710.1 Q9FWQ5 PAC:19658304 Arabidopsis thaliana 1706  
AT1G16710.2 F4I4I8 PAC:19658305 Arabidopsis thaliana 1677  
AT1G79000.1 Q9C5X9 PAC:19652295 Arabidopsis thaliana 1697  
AT1G67220.1 Q9FYH1 PAC:19655428 Arabidopsis thaliana 1367  
AT1G79000.2 F4IDH2 PAC:19652294 Arabidopsis thaliana 1741  
AT1G55970.1 A0A1P8AQG0 PAC:19658220 Arabidopsis thaliana 1456  
Thhalv10019887m V4M1M4 PAC:20183497 Eutrema salsugineum 1666  
Thhalv10006544m V4MTJ6 PAC:20188711 Eutrema salsugineum 1644  
Thhalv10012306m V4MF12 PAC:20184380 Eutrema salsugineum 1271  
Thhalv10018000m V4KIY6 PAC:20190976 Eutrema salsugineum 1691  
Thhalv10019679m V4KG26 PAC:20191854 Eutrema salsugineum 1037  
Ciclev10010922m V4STJ8 PAC:20797843 Citrus clementina 1325  
Ciclev10027675m V4UGH5 PAC:20814543 Citrus clementina 1763  
Ciclev10027674m V4RUQ7 PAC:20814542 Citrus clementina 1766  
Lus10033321 PAC:23172167 Linum usitatissimum 1594  
Lus10033319 PAC:23172237 Linum usitatissimum 1674  
Lus10034780 PAC:23142193 Linum usitatissimum 1703  

8 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17272723
            17046836
            18568037
            11701890
            16287980
            11359896
            15313412
            15313417