Protein Domain : IPR004811

Type:  Family Name:  RelA/SpoT family
Description:  The functions of Escherichia coliRelA and SpoT differ somewhat. RelA () produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT is a bifunctional enzyme; it degrades ppGpp, but can also act as a ppGpp synthetase. The two proteins are strongly similar. In many species, a single homologue to SpoT and RelA appears responsible for both ppGpp synthesis and ppGpp degradation [, ]. (p)ppGpp (alarmone) is a regulatory metabolite of the stringent response, which is characterised by growth arrest and the modulation of gene expression in response to various nutritional stresses []. Short Name:  RelA/Spo_fam
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0 Child Features

4 Contains

DB identifier Type Name
IPR004095 Domain TGS
IPR006674 Domain HD domain
IPR007685 Domain RelA/SpoT
IPR002912 Domain ACT domain

1 Cross References

Identifier
TIGR00691

0 Found In

1 GO Annotation

GO Term Gene Name
GO:0015969 IPR004811

1 Ontology Annotations

GO Term Gene Name
GO:0015969 IPR004811

0 Parent Features

7 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1007401m.p PAC:33657449 Brachypodium distachyon Pangenome 605  
Brdisv1pangenome1008307m.p PAC:33657346 Brachypodium distachyon Pangenome 1024  
Brdisv1pangenome1009037m.p PAC:33659534 Brachypodium distachyon Pangenome 476  
Brdisv1pangenome1011772m.p PAC:33621435 Brachypodium distachyon Pangenome 646  
Brdisv1BdTR11A1045478m.p PAC:35690419 Brachypodium distachyon BdTR11a 602  
Brdisv1BdTR11A1042286m.p PAC:35694933 Brachypodium distachyon BdTR11a 605  
Brdisv1BdTR11A1040321m.p PAC:35691971 Brachypodium distachyon BdTR11a 561  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15866041
            9383190
            11545276