Protein Domain : IPR006674

Type:  Domain Name:  HD domain
Description:  The HD domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity []. These enzymes appear to be involved in the nucleic acid metabolism, signal transduction and possibly other functions in bacteria, archaea and eukaryotes.The fact that all the highly conserved residues in the HD superfamily are histidines or aspartates suggests that coordination of divalent cations is essential for the activity of these proteins []. Short Name:  HD_domain

1 Child Features

DB identifier Type Name
IPR006675 Domain HDIG domain

0 Contains

3 Cross Referencess

Identifier
PF01966
PF13023
G3DSA:1.10.3210.10

7 Found Ins

DB identifier Type Name
IPR004811 Family RelA/SpoT family
IPR017771 Family Cyanamide hydratase
IPR017705 Family Ribonuclease Y
IPR006261 Family Deoxyguanosinetriphosphate triphosphohydrolase
IPR020779 Family Deoxyguanosinetriphosphate triphosphohydrolase, proteobacteria
IPR020873 Family 3'-5' exoribonuclease YhaM
IPR010043 Family Bifunctional uridylyltransferase/uridylyl-removing enzyme

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Type Name
IPR003607 Domain HD/PDEase domain

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
231418 D8RFK0 PAC:15416682 Selaginella moellendorffii 218  
100367 D8RRX9 PAC:15421797 Selaginella moellendorffii 542  
232413 D8RUG1 PAC:15419615 Selaginella moellendorffii 348  
102606 D8RVB9 PAC:15407447 Selaginella moellendorffii 455  
79872 D8QWM7 PAC:15405221 Selaginella moellendorffii 390  
106890 D8S220 PAC:15420952 Selaginella moellendorffii 480  
230378 D8R029 PAC:15413210 Selaginella moellendorffii 460  
89270 D8RBF9 PAC:15407788 Selaginella moellendorffii 750  
91657 D8RE77 PAC:15417066 Selaginella moellendorffii 213  
evm.model.supercontig_0.135 PAC:16403842 Carica papaya 247  
evm.model.supercontig_0.136 PAC:16403843 Carica papaya 171  
evm.model.supercontig_1.250 PAC:16404178 Carica papaya 351  
evm.model.supercontig_1440.2 PAC:16409056 Carica papaya 221  
evm.model.supercontig_151.24 PAC:16409541 Carica papaya 751  
evm.model.supercontig_39.93 PAC:16419108 Carica papaya 481  
evm.model.supercontig_48.137 PAC:16420770 Carica papaya 687  
evm.model.supercontig_589.3 PAC:16423102 Carica papaya 396  
evm.model.supercontig_69.27 PAC:16424895 Carica papaya 286  
evm.model.supercontig_69.28 PAC:16424896 Carica papaya 140  
evm.model.supercontig_75.94 PAC:16425938 Carica papaya 180  
evm.model.supercontig_78.51 PAC:16426229 Carica papaya 275  
evm.model.supercontig_80.8 PAC:16426807 Carica papaya 278  
29706.m001275 B9S5Q2 PAC:16806289 Ricinus communis 608  
29792.m000617 B9SVN0 PAC:16808651 Ricinus communis 109  
29822.m003343 B9RUU0 PAC:16809713 Ricinus communis 421  
29986.m001651 B9SAV1 PAC:16815149 Ricinus communis 887  
30073.m002237 B9S1Z6 PAC:16816822 Ricinus communis 806  
30094.m000682 B9SCQ5 PAC:16817599 Ricinus communis 223  
30128.m008887 B9RFG9 PAC:16818473 Ricinus communis 615  
30138.m003836 B9RLA4 PAC:16819207 Ricinus communis 262  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9868367
            17951247