Protein Domain : IPR004652

Type:  Family Name:  tRNA-dihydrouridine synthase, TIM-barrel, NifR3
Description:  This family represents one branch of (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family) and includes NifR3 itself, from Rhodobacter capsulatus. Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes [], and also in some archaea. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. Short Name:  tRNA_dU_NifR3
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0 Child Features

2 Contains

DB identifier Type Name
IPR013785 Domain Aldolase-type TIM barrel
IPR018517 Conserved_site tRNA-dihydrouridine synthase, conserved site

1 Cross References

Identifier
TIGR00737

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016491 IPR004652
GO:0050660 IPR004652
GO:0008033 IPR004652
GO:0055114 IPR004652

4 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR004652
GO:0050660 IPR004652
GO:0008033 IPR004652
GO:0055114 IPR004652

1 Parent Features

DB identifier Type Name
IPR001269 Family tRNA-dihydrouridine synthase

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1010601m.p PAC:33599018 Brachypodium distachyon Pangenome 345  
Zosma07g01350 PAC:50101894 Zostera marina 715  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12003496