GO Term : GO:0008009 chemokine activity GO

Namespace:  molecular_function Obsolete:  false
description  The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

139 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0008009 evm.TU.supercontig_28.122  
OntologyAnnotation GO:0008009 evm.model.supercontig_28.122 GO
OntologyAnnotation GO:0008009 Gorai.012G035700.1 GO
GOAnnotation GO:0008009 Gorai.012G035700  
GOAnnotation GO:0008009 Thecc1EG045675  
OntologyAnnotation GO:0008009 Thecc1EG045675t1 GO
GOAnnotation GO:0008009 Araha.21851s0001  
OntologyAnnotation GO:0008009 Araha.21851s0001.1.p GO
OntologyAnnotation GO:0008009 Medtr1g046150.1 GO
GOAnnotation GO:0008009 Medtr1g046150  
GOAnnotation GO:0008009 Medtr5g072325  
OntologyAnnotation GO:0008009 Medtr5g072325.1 GO
GOAnnotation GO:0008009 Medtr5g459310  
OntologyAnnotation GO:0008009 Medtr5g459310.1 GO
OntologyAnnotation GO:0008009 SapurV1A.0049s0130.1.p GO
GOAnnotation GO:0008009 SapurV1A.0049s0130  
GOAnnotation GO:0008009 Traes_3B_AB077D149  
OntologyAnnotation GO:0008009 Traes_3B_AB077D149.4 GO
OntologyAnnotation GO:0008009 Traes_5AL_A962076C8.12 GO
GOAnnotation GO:0008009 Traes_5AL_A962076C8  
OntologyAnnotation GO:0008009 Prupe.5G077300.1.p GO
GOAnnotation GO:0008009 Prupe.5G077300  
OntologyAnnotation GO:0008009 Bradi2g19705.1.p GO
GOAnnotation GO:0008009 Bradi2g19705  
GOAnnotation GO:0008009 Tp57577_TGAC_v2_gene26276  
OntologyAnnotation GO:0008009 Tp57577_TGAC_v2_mRNA27175 GO
GOAnnotation GO:0008009 Pavir.1NG425800  
OntologyAnnotation GO:0008009 Pavir.1NG425800.1.p GO
OntologyAnnotation GO:0008009 Oeu062681.1 GO
GOAnnotation GO:0008009 Oeu062681.1  

27 Parents

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0048870 cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GO:0006935 chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0005102 receptor binding Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0008009 chemokine activity The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0006928 movement of cell or subcellular component The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
GO:0005125 cytokine activity Functions to control the survival, growth, differentiation and effector function of tissues and cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0005126 cytokine receptor binding Interacting selectively and non-covalently with a cytokine receptor.
GO:0051674 localization of cell Any process in which a cell is transported to, and/or maintained in, a specific location.
GO:0040011 locomotion Self-propelled movement of a cell or organism from one location to another.
GO:0001664 G-protein coupled receptor binding Interacting selectively and non-covalently with a G-protein coupled receptor.
GO:0016477 cell migration The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
GO:0042330 taxis The directed movement of a motile cell or organism in response to an external stimulus.
GO:0060326 cell chemotaxis The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0042379 chemokine receptor binding Interacting selectively and non-covalently with any chemokine receptor.

33 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0060326 GO:0008009
is_a GO:0042379 GO:0008009
is_a GO:0005125 GO:0008009
part of GO:0009605 GO:0008009
part of GO:0051674 GO:0008009
part of GO:0051179 GO:0008009
part of GO:0048870 GO:0008009
part of GO:0006935 GO:0008009
is_a GO:0001664 GO:0008009
part of GO:0006928 GO:0008009
is_a GO:0005515 GO:0008009
part of GO:0070887 GO:0008009
part of GO:0016477 GO:0008009
part of GO:0050896 GO:0008009
is_a GO:0005126 GO:0008009
is_a GO:0005488 GO:0008009
is_a GO:0003674 GO:0008009
part of GO:0040011 GO:0008009
is_a GO:0005102 GO:0008009
part of GO:0008150 GO:0008009
part of GO:0051716 GO:0008009
part of GO:0042330 GO:0008009
part of GO:0042221 GO:0008009
part of GO:0009987 GO:0008009
part of GO:0044763 GO:0008009
part of GO:0044699 GO:0008009
negatively regulates GO:0008009 GO:0039553
regulates GO:0008009 GO:0039553
regulates GO:0008009 GO:1900136
regulates GO:0008009 GO:1900136

0 Synonyms