Protein Domain : IPR009017

Type:  Domain Name:  Green fluorescent protein
Description:  The green fluorescent-like protein family consists of fluorescent proteins and non-fluorescent chromoproteins, derived from several species of Cnidarians, as well as certain diazotrophic bacteria [, ]. These proteins range in their absorption wavelength maximum, and are often classified by their colour: green, yellow, red and purple-blue. These colour differences arise from changes in the structure of the chromophore, which is generated internally by auto-catalysis. The chromophore comprises Ser65-Tyr66-Gly67 in Aequorea victoria(Jellyfish), which forms a five-member ring after its modification. In the bioluminescent organism A. victoria, GFP acts to transform the blue light emitted from aequorin into green light. However, most organisms with GFP-like molecules are not bioluminescent, and in some cases are not even fluorescent. These proteins all display a beta-can structure, which surrounds the chromophore and acts to shield it against quenching agents. The G2 domain of nidogen contains a beta-can structure that exhibits extraordinary similarity to GFP, even though their sequences show only low sequence identity []. Nidogen is a component of basement membranes, whose interactions with other basement membrane proteins contribute to the assembly and function of the basement membrane. The G2 domain serves as a protein-binding module. The structure is similar enough between GFP and the G2 domain of nidogen to suggest a common ancestral origin. Short Name:  GFP
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2 Child Features

DB identifier Type Name
IPR023413 Domain Green fluorescent protein-like
IPR006605 Domain G2 nidogen/fibulin G2F

0 Contains

1 Cross References

Identifier
SSF54511

2 Found Ins

DB identifier Type Name
IPR000786 Family Green fluorescent protein, GFP
IPR011584 Family Green fluorescent protein-related

0 GO Annotation

0 Ontology Annotations

0 Parent Features

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Ciclev10033604m V4T8J2 PAC:20803883 Citrus clementina 104  
Brdisv1Gaz-81009087m.p PAC:33811562 Brachypodium distachyon Gaz-8 84  
Sp3g24530.1 PAC:45087092 Schrenkiella parvula 349  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11427896
            11929996
            12502888