Protein Domain : IPR004508

Type:  Family Name:  Thioredoxin-independent 5'-adenylylsulphate reductase
Description:  This enzyme, involved in the assimilation of inorganic sulphate, is closely related to the thioredoxin-dependent PAPS reductase of Bacteria (CysH) and Saccharomyces cerevisiae. However, it has its own C-terminal thioredoxin-like domain and is not thioredoxin-dependent. Also, it has a substrate preference for 5'-adenylylsulphate (APS) over 3'-phosphoadenylylsulphate (PAPS) so the pathway does not require an APS kinase (CysC) to convert APS to PAPS. Arabidopsis thalianaappears to have three isozymes, all able to complement Escherichia coliCysH mutants (even in backgrounds lacking thioredoxin or APS kinase) but likely localized to different compartments in Arabidopsis. Short Name:  Thioredoxin-indep_APS_Rdtase
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0 Child Features

3 Contains

DB identifier Type Name
IPR013766 Domain Thioredoxin domain
IPR002500 Domain Phosphoadenosine phosphosulphate reductase
IPR014729 Domain Rossmann-like alpha/beta/alpha sandwich fold

1 Cross References

Identifier
TIGR00424

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016671 IPR004508
GO:0019419 IPR004508
GO:0055114 IPR004508

3 Ontology Annotations

GO Term Gene Name
GO:0016671 IPR004508
GO:0019419 IPR004508
GO:0055114 IPR004508

0 Parent Features

590 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
evm.model.supercontig_12.288 PAC:16406845 Carica papaya 464  
evm.model.supercontig_12.285 PAC:16406842 Carica papaya 450  
evm.model.supercontig_152.28 PAC:16409611 Carica papaya 463  
29842.m003580 B9RXK0 PAC:16810713 Ricinus communis 471  
Cucsa.045160.1 PAC:16953318 Cucumis sativus 463  
Cucsa.085750.1 PAC:16956691 Cucumis sativus 461  
orange1.1g012415m A0A067GS78 PAC:18112884 Citrus sinensis 464  
orange1.1g012452m A0A067GEZ0 PAC:18112885 Citrus sinensis 463  
orange1.1g015013m A0A067GF89 PAC:18112886 Citrus sinensis 414  
orange1.1g018045m A0A067GHY7 PAC:18112887 Citrus sinensis 361  
orange1.1g022560m A0A067GSI7 PAC:18112888 Citrus sinensis 295  
orange1.1g012424m A0A067GS78 PAC:18112883 Citrus sinensis 464  
orange1.1g042284m A0A067FH38 PAC:18108637 Citrus sinensis 430  
AT4G04610.1 P92979 PAC:19646218 Arabidopsis thaliana 465  
AT4G21990.1 P92980 PAC:19645218 Arabidopsis thaliana 458  
AT4G21990.2 F4JKD5 PAC:19645219 Arabidopsis thaliana 340  
AT1G62180.1 P92981 PAC:19655489 Arabidopsis thaliana 454  
AT1G62180.2 F4HX50 PAC:19655490 Arabidopsis thaliana 447  
Thhalv10028642m V4L3C0 PAC:20198032 Eutrema salsugineum 464  
Thhalv10023459m V4JUZ5 PAC:20201691 Eutrema salsugineum 458  
Ciclev10010222m V4TYK4 PAC:20795732 Citrus clementina 426  
Ciclev10015166m V4W9L7 PAC:20815070 Citrus clementina 463  
Ciclev10015152m V4UFN4 PAC:20815068 Citrus clementina 464  
Ciclev10015202m V4TR19 PAC:20815071 Citrus clementina 455  
Ciclev10015162m V4UFN4 PAC:20815069 Citrus clementina 464  
Lus10020040 PAC:23156245 Linum usitatissimum 461  
Lus10015560 PAC:23173685 Linum usitatissimum 411  
Potri.T104400.1 PAC:27003374 Populus trichocarpa 466  
Potri.T104400.2 A0A2K1R6N2 PAC:27003375 Populus trichocarpa 465  
Potri.004G012100.1 A0A2K2ANB3 PAC:26991255 Populus trichocarpa 465  

0 Publications