Type: | Domain | Name: | I/LWEQ domain |
Description: | I/LWEQ domains bind to actin. It has been shown that the I/LWEQ domains from mouse talin and yeast Sla2p interact with F-actin []. The domain has four conserved blocks, the name of the domain is derived from the initial conserved amino acid of each of the four blocks []. I/LWEQ domains can beplaced into four major groups based on sequence similarity: Metazoan talin.Dictyostelium discoideum(Slime mould) TalA/TalB.Metazoan Huntingtin-interacting protein-1 related (HIP1R) [].Saccharomyces cerevisiaeSla2p. | Short Name: | ILWEQ_dom |