Protein Domain : IPR008977

Type:  Domain Name:  PHM/PNGase F domain
Description:  Peptidyl-glycine alpha-amidating monooxygenase (PAM) is involved in the amidation of of bioactive peptides. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL), each of which binds one copper atom []. This entry represents the PHM domain of PAM, and related catalytic domains found in other copper type II ascorbate-dependent monooxygenases, such as dopamine-beta-monooxygenase, and in peptide:N-glycosidase F (PNGase F). Short Name:  PHM/PNGase_F_dom
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0 Child Features

2 Contains

DB identifier Type Name
IPR014783 Conserved_site Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site
IPR020611 Conserved_site Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site

1 Cross References

Identifier
SSF49742

2 Found Ins

DB identifier Type Name
IPR000720 Family Peptidyl-glycine alpha-amidating monooxygenase
IPR000945 Family Dopamine beta-hydroxylase-related

1 GO Annotation

GO Term Gene Name
GO:0003824 IPR008977

1 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR008977

0 Parent Features

55 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
65252 I0Z484 PAC:27389712 Coccomyxa subellipsoidea C-169 718  
60312 C1MXW4 PAC:27338872 Micromonas pusilla CCMP1545 209  
60313 C1MXW5 PAC:27338781 Micromonas pusilla CCMP1545 794  
50858 C1E9M3 PAC:27404129 Micromonas sp RCC299 407  
61406 C1ECG1 PAC:27401405 Micromonas sp RCC299 540  
15206 A4RWP3 PAC:27415678 Ostreococcus lucimarinus 774  
Cre10.g422500.t1.1 A0A2K3D997 PAC:30790002 Chlamydomonas reinhardtii 1025  
Cre10.g465700.t1.2 A0A2K3DC83 PAC:30790103 Chlamydomonas reinhardtii 1023  
Cre12.g557078.t1.1 A0A2K3D752 PAC:30792350 Chlamydomonas reinhardtii 884  
Cre03.g152850.t1.2 A0A0S2C767 PAC:30787184 Chlamydomonas reinhardtii 926  
Cre03.g201300.t1.1 A0A2K3DZF2 PAC:30786822 Chlamydomonas reinhardtii 635  
Cre06.g278103.t1.1 A0A2K3DNU6 PAC:30779554 Chlamydomonas reinhardtii 650  
Zosma99g00080.1 A0A0K9NHH5 PAC:33182692 Zostera marina 272  
Dusal.0149s00022.2.p PAC:33186633 Dunaliella salina 607  
Dusal.0149s00022.1.p PAC:33186632 Dunaliella salina 802  
Brdisv1BdTR7a1042554m.p PAC:33375151 Brachypodium distachyon BdTR7a 78  
Brdisv20Bd21Ref1046831m.p PAC:33461817 Brachypodium distachyon Bd21 AnntCtrl 78  
Brdisv1ABR9_r1034506m.p PAC:33550593 Brachypodium distachyon ABR9 78  
Brdisv1pangenome1060033m.p PAC:33638866 Brachypodium distachyon Pangenome 78  
Brdisv1Tek-21042791m.p PAC:33924461 Brachypodium distachyon Tek-2 78  
Brdisv1Bd29-11040137m.p PAC:34140386 Brachypodium distachyon Bd29-1 78  
Brdisv1BdTR8i1041638m.p PAC:34237206 Brachypodium distachyon BdTR8i 78  
Brdisv1Bd1-11041830m.p PAC:34284186 Brachypodium distachyon Bd1-1 78  
Brdisv1Mon31043348m.p PAC:34306478 Brachypodium distachyon Mon3 78  
Brdisv1BdTR12c1041582m.p PAC:34403976 Brachypodium distachyon BdTR12c 138  
Brdisv1Arn11043692m.p PAC:34552629 Brachypodium distachyon Arn1 78  
Brdisv1Bd21Control1044895m.p PAC:34790487 Brachypodium distachyon Bd21 AsmbCtrl 78  
Kaladp0062s0106.1.p PAC:35781934 Kalanchoe fedtschenkoi 165  
Pum0144s0004.1.p A0A1X6P9F3 PAC:38016413 Porphyra umbilicalis 894  
Pum2421s0001.1.p A0A1X6NJ62 PAC:38007646 Porphyra umbilicalis 442  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10504734