GO Term : GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

35 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0008750 187398 GO
GOAnnotation GO:0008750 gm1.4519_g  
OntologyAnnotation GO:0008750 187400 GO
GOAnnotation GO:0008750 gm1.4521_g  
GOAnnotation GO:0008750 MicpuC2.SAR_estExt_Genewise1Plus.C_90179  
OntologyAnnotation GO:0008750 70229 GO
GOAnnotation GO:0008750 EuGene.0100010844  
OntologyAnnotation GO:0008750 55617 GO
GOAnnotation GO:0008750 Cre01.g054500  
OntologyAnnotation GO:0008750 Cre01.g054500.t1.2 GO
GOAnnotation GO:0008750 Brdisv1pangenome1008364m.g  
OntologyAnnotation GO:0008750 Brdisv1pangenome1008364m.p GO
GOAnnotation GO:0008750 Brdisv1pangenome1009342m.g  
OntologyAnnotation GO:0008750 Brdisv1pangenome1009342m.p GO
OntologyAnnotation GO:0008750 Brdisv1pangenome1013239m.p GO
GOAnnotation GO:0008750 Brdisv1pangenome1013239m.g  
OntologyAnnotation GO:0008750 Brdisv1BdTR12c1040018m.p GO
GOAnnotation GO:0008750 Brdisv1BdTR12c1040018m.g  
OntologyAnnotation GO:0008750 Brdisv1BdTR11A1037371m.p GO
GOAnnotation GO:0008750 Brdisv1BdTR11A1037371m.g  
OntologyAnnotation GO:0008750 Brdisv1BdTR11A1044002m.p GO
GOAnnotation GO:0008750 Brdisv1BdTR11A1044002m.g  
GOAnnotation GO:0008750 Brdisv1BdTR11A1046165m.g  
OntologyAnnotation GO:0008750 Brdisv1BdTR11A1046165m.p GO
GOAnnotation GO:0008750 Pum0022s0039  
OntologyAnnotation GO:0008750 Pum0022s0039.1.p GO
GOAnnotation GO:0008750 Cz03g01040  
OntologyAnnotation GO:0008750 Cz03g01040.t1 GO
GOAnnotation GO:0008750 Bobra.4_1s0147  
OntologyAnnotation GO:0008750 Bobra.4_1s0147.1.p GO

12 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016651 oxidoreductase activity, acting on NAD(P)H Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.
GO:0008746 NAD(P)+ transhydrogenase activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.

11 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008746 GO:0008750
is_a GO:0016491 GO:0008750
is_a GO:0003824 GO:0008750
part of GO:0055114 GO:0008750
part of GO:0044710 GO:0008750
part of GO:0044699 GO:0008750
is_a GO:0016652 GO:0008750
is_a GO:0003674 GO:0008750
part of GO:0008152 GO:0008750
is_a GO:0016651 GO:0008750
part of GO:0008150 GO:0008750

4 Synonyms

Name Type
NAD(P) transhydrogenase (AB-specific) activity synonym
NADPH:NAD+ oxidoreductase (AB-specific) synonym
pyridine nucleotide transhydrogenase activity synonym
transhydrogenase activity synonym