Protein Domain : IPR026257

Type:  Family Name:  FK506-binding protein
Description:  FK506-binding proteins (FKBPs) are a particular class of peptidyl-prolyl cis-trans isomerases (PPIases). They are the intracellular receptors for two immunosuppressive compounds, rapamycin and FK506. PPIases are thought to act in conjunction with protein chaperones because they accelerate the rate of conformational interconversions around proline residues in polypeptides []. In Saccharomyces cerevisiae, FKBPs locate in nucleolus and interact with NOP53, which is is a novel nucleolar 60S ribosomal subunit biogenesis protein []. Short Name:  FK506_BP
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0 Child Features

0 Contains

1 Cross References

Identifier
PIRSF001473

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0003755 IPR026257
GO:0005528 IPR026257
GO:0000412 IPR026257
GO:0018208 IPR026257
GO:0005730 IPR026257

5 Ontology Annotations

GO Term Gene Name
GO:0003755 IPR026257
GO:0005528 IPR026257
GO:0000412 IPR026257
GO:0018208 IPR026257
GO:0005730 IPR026257

1 Parent Features

DB identifier Type Name
IPR023566 Family Peptidyl-prolyl cis-trans isomerase, FKBP-type

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
AUR62016106-RA PAC:36288662 Chenopodium quinoa 410  
CepurR40.9G000300.1.p PAC:43001543 Ceratodon purpureus R40 415  
CepurGG1.9G000300.1.p PAC:43062608 Ceratodon purpureus GG1 415  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            15686447
            7525596