GO Term : GO:0008705 methionine synthase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

133 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0008705 31475.t000002  
OntologyAnnotation GO:0008705 31475.m000027 GO
GOAnnotation GO:0008705 e_gw1.1.2031.1  
OntologyAnnotation GO:0008705 148156 GO
GOAnnotation GO:0008705 estExt_fgenesh2_pg.C_Chr_070319  
OntologyAnnotation GO:0008705 105867 GO
GOAnnotation GO:0008705 estExt_GenewiseEukaryote.C_Chr_30022  
OntologyAnnotation GO:0008705 45056 GO
GOAnnotation GO:0008705 Glyma.07G223600  
OntologyAnnotation GO:0008705 Glyma.07G223600.1.p GO
OntologyAnnotation GO:0008705 Glyma.20G023400.1.p GO
GOAnnotation GO:0008705 Glyma.20G023400  
GOAnnotation GO:0008705 Cre06.g250902  
OntologyAnnotation GO:0008705 Cre06.g250902.t1.1 GO
GOAnnotation GO:0008705 Medtr8g005120  
OntologyAnnotation GO:0008705 Medtr8g005120.1 GO
GOAnnotation GO:0008705 Traes_3B_31C92ED65  
OntologyAnnotation GO:0008705 Traes_3B_31C92ED65.1 GO
OntologyAnnotation GO:0008705 Traes_4DL_6F717C706.3 GO
GOAnnotation GO:0008705 Traes_4DL_6F717C706  
GOAnnotation GO:0008705 Pp3c17_1430  
OntologyAnnotation GO:0008705 Pp3c17_1430V3.1.p GO
OntologyAnnotation GO:0008705 Pp3c17_1430V3.2.p GO
GOAnnotation GO:0008705 Aqcoe5G043500  
OntologyAnnotation GO:0008705 Aqcoe5G043500.1.p GO
GOAnnotation GO:0008705 Dusal.0126s00011  
OntologyAnnotation GO:0008705 Dusal.0126s00011.2.p GO
GOAnnotation GO:0008705 Brdisv1Tek-41031686m.g  
OntologyAnnotation GO:0008705 Brdisv1Tek-41031686m.p GO
GOAnnotation GO:0008705 Brdisv1pangenome1007940m.g  

44 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0006555 methionine metabolic process The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006520 cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0008652 cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
GO:0009086 methionine biosynthetic process The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006082 organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.
GO:0006790 sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0008705 methionine synthase activity Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.
GO:0009067 aspartate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0044711 single-organism biosynthetic process A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
GO:0043436 oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

43 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042084 GO:0008705
part of GO:0009086 GO:0008705
is_a GO:0008172 GO:0008705
part of GO:0032259 GO:0008705
part of GO:0006520 GO:0008705
part of GO:1901605 GO:0008705
part of GO:1901607 GO:0008705
part of GO:0044281 GO:0008705
part of GO:0016053 GO:0008705
is_a GO:0003674 GO:0008705
part of GO:0006807 GO:0008705
part of GO:0044237 GO:0008705
part of GO:0044699 GO:0008705
part of GO:0044710 GO:0008705
part of GO:0044238 GO:0008705
part of GO:0044711 GO:0008705
is_a GO:0008168 GO:0008705
part of GO:0008150 GO:0008705
part of GO:0071704 GO:0008705
part of GO:0009067 GO:0008705
part of GO:0009066 GO:0008705
part of GO:0044272 GO:0008705
part of GO:0006790 GO:0008705
part of GO:0008152 GO:0008705
part of GO:0008652 GO:0008705
part of GO:0000097 GO:0008705
part of GO:0000096 GO:0008705
part of GO:1901576 GO:0008705
part of GO:0006555 GO:0008705
part of GO:0009987 GO:0008705

21 Synonyms

Name Type
tetrahydropteroylglutamic methyltransferase activity synonym
vitamin B12 methyltransferase activity synonym
5-methyltetrahydrofolate--homocysteine S-methyltransferase activity synonym
5-methyltetrahydrofolate--homocysteine transmethylase activity synonym
5-methyltetrahydrofolate-homocysteine S-methyltransferase activity synonym
5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity synonym
B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity synonym
B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity synonym
cobalamin-dependent methionine synthase activity synonym
MetH synonym
methionine synthase (cobalamin-dependent) activity synonym
methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity synonym
N(5)-methyltetrahydrofolate methyltransferase activity synonym
N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity synonym
N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity synonym
N-methyltetrahydrofolate:L-homocysteine methyltransferase activity synonym
N5-methyltetrahydrofolate methyltransferase activity synonym
N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity synonym
N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity synonym
tetrahydrofolate methyltransferase activity synonym
tetrahydropteroylglutamate methyltransferase activity synonym